Common painkiller tested against rare brain tumors

NCT ID NCT03079999

Ongoing Disease control Sponsor: Massachusetts Eye and Ear Infirmary Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests whether aspirin can delay tumor growth and maintain hearing in people with vestibular schwannoma (acoustic neuroma), a non-cancerous brain tumor. About 97 participants are randomly assigned to take aspirin or a placebo twice daily. The study tracks how long it takes for the tumor to grow more than 20%.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aspirin
What this could lead to: If it works, aspirin could offer a simple, low-cost way to slow tumor growth and protect hearing in people with vestibular schwannomas.
What could go wrong: This is a mid-stage trial with only 97 participants, so results may not be conclusive. Aspirin also carries risks like stomach bleeding, and it may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACOUSTIC NEUROMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acoustic neuroma Neurofibromatosis 2 NF2-related schwannomatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACOUSTIC NEUROMA NEUROFIBROMATOSIS 2 VESTIBULAR SCHWANNOMA

Contacts and locations

Locations

Massachusetts Eye and Ear

Boston, Massachusetts, 02114, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Stanford Otolaryngology/HNS

Stanford, California, 94304, United States
University of Miami

Miami, Florida, 33136, United States
University of Utah

Salt Lake City, Utah, 84101, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.