Common painkiller tested against rare brain tumors

NCT ID NCT03079999

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests whether aspirin can delay tumor growth and maintain hearing in people with vestibular schwannoma (acoustic neuroma), a non-cancerous brain tumor. About 97 participants are randomly assigned to take aspirin or a placebo twice daily. The study tracks how long it takes for the tumor to grow more than 20%.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aspirin

What this could lead to

If it works, aspirin could offer a simple, low-cost way to slow tumor growth and protect hearing in people with vestibular schwannomas.

What could go wrong

This is a mid-stage trial with only 97 participants, so results may not be conclusive. Aspirin also carries risks like stomach bleeding, and it may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acoustic neuroma Neurofibromatosis 2 NF2-related schwannomatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts Eye and Ear

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Stanford Otolaryngology/HNS

    Stanford, California, 94304, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Utah

    Salt Lake City, Utah, 84101, United States