Could a probiotic help save sight in diabetes?
NCT ID NCT07383701
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether a daily probiotic supplement (Lactobacillus plantarum 299v) can reduce retinal swelling and improve vision in people with diabetic macular edema. Thirty-six participants will take the probiotic twice daily for four months. Researchers will measure changes in retinal thickness, visual acuity, and the need for anti-VEGF injections, comparing results to historical data.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lactobacillus plantarum 299v probiotic
What this could lead to
If it works, this could offer a simple, safe supplement to help control diabetic macular edema and reduce the need for eye injections.
What could go wrong
This is a small, early pilot study with only 36 people, and it compares results to past data rather than a current placebo group. The probiotic may not improve vision or reduce swelling.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIABETIC MACULAR EDEMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Mass Eye and Ear
Boston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact