Eye surgery breakthrough? tiny trial tests humira injection during corneal implant

NCT ID NCT06926478

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial will test whether injecting adalimumab (Humira) into the eye during Boston KPro surgery is safe for 8 patients with severe corneal damage. The study focuses on side effects and tolerability, not yet on how well it works. It is for people who have run out of other options for corneal transplants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

adalimumab (Humira) injection

What this could lead to

If safe, this could point toward a way to reduce inflammation and improve outcomes after complex corneal implant surgery.

What could go wrong

This is a very early, tiny trial (8 people) focused only on short-term safety. It is not designed to prove the drug works, and unexpected side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ocular cicatricial pemphigoid Pemphigoid, Benign Mucous Membrane Stevens-Johnson syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts Eye and Ear

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact