Promising drug tackles rare eye disease that leads to blindness

NCT ID NCT00584935

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested the drug rituximab in 3 people with ocular cicatricial pemphigoid, a rare autoimmune disease that causes scarring in the eye and can lead to blindness. The goal was to see if the drug could stop further scarring when standard treatments had failed. The study measured scarring and side effects over several weeks.

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Conditions

The condition(s) this trial relates to.

blindness (disorder) bullous pemphigoid ocular cicatricial pemphigoid Pemphigoid, Benign Mucous Membrane

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States