Could a light treatment for donor eyes save more sight?
NCT ID NCT06753916
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether treating donor corneal tissue with a special light-based process (cross-linking) before transplant can make it last longer and reduce rejection in people at high risk of graft failure. About 96 adults who need a high-risk cornea transplant will receive either a treated or standard donor cornea. The main goal is to check safety and see if the treated tissue lowers the chance of rejection or graft failure over two years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Cincinnati Eye Institute
RECRUITINGCincinnati, Ohio, 45242, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke University - Duke Eye Center
RECRUITINGDurham, North Carolina, 27705, United States
Contact
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kansas City Eye Clinic
RECRUITINGOverland Park, Kansas, 66204, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts Eye and Ear
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Mid-Atlantic Cornea Consultant
NOT_YET_RECRUITINGTowson, Maryland, 21204, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Price Vision Group
RECRUITINGIndianapolis, Indiana, 46260, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of California Los Angeles - Doris Stein Eye Research Center
NOT_YET_RECRUITINGLos Angeles, California, 90095, United States
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University of California Irvine - Gavin Herbert Eye Institute
NOT_YET_RECRUITINGIrvine, California, 92617, United States
Contact
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University of California San Francisco - Wayne and Gladys Valley Center for Vision
NOT_YET_RECRUITINGSan Francisco, California, 94158, United States
Contact Email: •••••@•••••
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University of Miami - Bascom Palmer Eye Institute
RECRUITINGMiami, Florida, 33136, United States
Contact
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University of Michigan - Kellogg Eye Center
RECRUITINGAnn Arbor, Michigan, 48015, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wake Forest Baptist Eye Center
NOT_YET_RECRUITINGBermuda Run, North Carolina, 27006, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact