Could a single injection replace weeks of eye drops after retinal surgery?

NCT ID NCT05331664

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a steroid injection given during retinal detachment surgery can replace the usual course of antibiotic and steroid eye drops afterward. About 168 adults with a first-time retinal detachment will receive either the injection or standard drops. The goal is to see if the injection controls inflammation just as well, potentially simplifying recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

triamcinolone acetonide (Kenalog-40) injection

What this could lead to

If successful, this could simplify recovery after retinal detachment surgery by eliminating the need for daily eye drops, making it easier for patients to follow treatment.

What could go wrong

This is a Phase 4 trial with 168 participants, so results may not apply to everyone. There is a risk that the injection may not control inflammation as well as drops, requiring rescue medication.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RHEGMATOGENOUS RETINAL DETACHMENT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Inflammation rhegmatogenous retinal detachment

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts Eye and Ear

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••