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Scientists scan brains to unravel voice disorders

NCT ID NCT05216770

Recruiting now Knowledge-focused Sponsor: Massachusetts Eye and Ear Infirmary Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses brain scans (fMRI, MEG, EEG) and a numbing throat spray to understand what goes wrong in the brains of people with laryngeal dystonia or voice tremor. Researchers will compare brain activity between these groups and healthy volunteers. The goal is to find unique brain markers for each condition, which could lead to better treatments down the road.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
topical bupivacaine (numbing spray)
What this could lead to
If successful, this could help identify specific brain markers for each condition, potentially guiding more targeted treatments in the future.
What could go wrong
This is a very early, small study focused on understanding brain activity, not testing a treatment. The numbing spray is used only temporarily to study its effect on symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

essential tremor spasmodic dystonia Tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LARYNGEAL DYSTONIA SPASMODIC DYSPHONIA TREMOR

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts Eye and Ear and University of California San Francisco

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

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