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Could magnetic pulses to the brain ease a rare voice disorder?

NCT ID NCT07683767

Symptom relief Sponsor: Universidade Federal de Pernambuco Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can improve voice quality in people with laryngeal dystonia, a condition that causes involuntary muscle spasms in the voice box. Twenty adults with the condition will receive rTMS alone, rTMS combined with speech therapy, or a sham (fake) stimulation with speech therapy. Researchers will measure changes in voice quality, vocal effort, and overall improvement to see if this approach offers a new treatment option.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could point toward a non-invasive treatment option for voice problems in laryngeal dystonia.
What could go wrong
This is a small, early-stage trial with only 20 participants. The effects may be modest or not last long, and rTMS can cause mild side effects like headache or scalp discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years) of any sex with a confirmed diagnosis of laryngeal dystonia * Participants not undergoing botulinum toxin treatment at the time of the intervention * Ability to provide informed consent * Ability to complete all study assessments and intervention procedures Exclusion Criteria: * Other forms of dystonia * Vocal fold lesions * Vocal fold paralysis * Contraindications to repetitive transcranial magnetic stimulation (rTMS) * Inability to complete study assessments or intervention procedures

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Conditions

The condition(s) this trial relates to.

spasmodic dystonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laryngeal dystonia Spasmodic dysphonia

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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