Institut Cancerologie De L'ouest
Clinical trials sponsored by Institut Cancerologie De L'ouest, explained in plain language.
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Tailored chemo doses may help older pancreatic cancer patients maintain independence
Disease control CompletedThis study tested a personalized dosing approach for the chemotherapy combination FOLFIRINOX in 72 patients aged 70 and older with metastatic pancreatic cancer. The goal was to see if adjusting doses based on genetic markers could reduce severe side effects while still controllin…
Phase: PHASE2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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New combo therapy shows promise for prostate cancer with limited spread
Disease control CompletedThis study looked at 74 men with prostate cancer that had come back in up to 5 pelvic lymph nodes after initial treatment. They received high-dose radiation to the affected nodes along with hormone therapy. The goal was to see how long it would take for the cancer to progress aga…
Phase: PHASE2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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New imaging agent spots hidden breast cancer spread
Diagnosis CompletedThis study tested a new radioactive tracer called 89Zr-TLX250 that attaches to a protein (CAIX) found on some triple negative breast cancer cells. Twelve people with advanced triple negative breast cancer received the tracer and had a PET/CT scan. The researchers compared how man…
Phase: PHASE2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated May 17, 2026 04:47 UTC
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New scan may spot brain tumors better than MRI
Diagnosis CompletedThis study tested whether a special PET scan called DOPA PET/CT can find untreated brain metastases (cancer that spread to the brain) as well as or better than standard MRI. Researchers studied 32 adults with lung cancer, breast cancer, or melanoma who had at least one brain meta…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated May 17, 2026 04:44 UTC
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New scan could spot bladder cancer earlier
Diagnosis CompletedThis study tested a new imaging agent called 89Zr-girentuximab to see if it can help detect non-muscle-invasive bladder cancer (NMIBC) using PET/CT scans. Six adults with confirmed NMIBC received the agent and were monitored for safety and how well the scans could spot cancer cel…
Phase: EARLY_PHASE1 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated May 14, 2026 12:04 UTC
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Breathing support after surgery cuts lung risks in High-Risk patients
Prevention CompletedThis study tested whether giving patients a breathing mask (noninvasive ventilation) soon after surgery could prevent serious lung complications. It included 266 adults at high risk for lung problems, identified by a special score called ARISCAT. The goal was to see if this appro…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Prevention
Last updated May 11, 2026 20:52 UTC
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Quick fix for chemo line blockages: dye or X-Ray?
Symptom relief CompletedThis study looked at 92 adults with cancer who had a blocked central line (CVC) before chemotherapy. Researchers compared two methods to fix the blockage: injecting a contrast dye or using a chest X-ray followed by a saline flush. The goal was to see which method allowed doctors …
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 17, 2026 04:49 UTC
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Fat grafting before implant may ease pain and improve breast reconstruction results
Symptom relief CompletedThis study tested a breast reconstruction method for women who had a mastectomy (breast removal) due to cancer. Instead of placing the implant under the chest muscle, doctors first used fat grafting to prepare the skin and then placed the implant just under the skin. The goal was…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 17, 2026 04:49 UTC
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Pepper patch may beat pills for Post-Surgery breast cancer pain
Symptom relief CompletedThis study tested whether a capsaicin skin patch (made from chili peppers) works better than an oral pain medication (pregabalin) for nerve pain that starts soon after breast cancer surgery. 140 women who had surgery for breast cancer and developed nerve pain within 2 months were…
Phase: PHASE3 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 17, 2026 04:47 UTC
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Virtual reality goggles ease pain during cancer procedures
Symptom relief CompletedThis study tested whether using virtual reality (VR) during cancer surgeries done under local anesthesia can lower pain and anxiety. 42 adults with cancer took part. One group received standard local anesthesia, while the other also used a VR headset showing calming scenes. The g…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 17, 2026 04:42 UTC
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Exercise eases fatigue for cancer patients in new study
Symptom relief CompletedThis study looked at how a 12-week exercise program affects fatigue, quality of life, and fear of movement in 37 cancer patients. Participants had different types of cancer and treatments. The program aimed to help patients feel less tired and move more comfortably.
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Fat grafting offers natural breast reconstruction alternative
Symptom relief CompletedThis study tested a breast reconstruction method that uses only a patient's own fat (lipomodulin) instead of implants or tissue flaps. It included 118 women who had a mastectomy for breast cancer. The goal was to see how well the technique works, how the breast looks afterward, a…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Meditation audio eases breast biopsy stress, study finds
Symptom relief CompletedThis study looked at whether listening to a guided meditation audio during a breast biopsy can help patients feel less pain and anxiety. 225 people having a breast biopsy took part. They answered questionnaires about their pain and anxiety before and after the procedure. The goal…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated Apr 30, 2026 15:48 UTC
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Do brain radiotherapy masks mess up MRI scans? small study finds out
Knowledge-focused CompletedThis study looked at whether the special masks used to hold the head still during brain radiotherapy affect the quality of MRI scans needed for treatment planning. Three healthy volunteers had MRI scans with and without the masks to see if the masks caused any problems. The goal …
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 17, 2026 04:44 UTC
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New study reveals how breast reconstruction technique affects pain and recovery
Knowledge-focused CompletedThis study looked at 27 women with breast cancer who had a mastectomy and immediate breast reconstruction using an implant. The implant was placed either above or below the chest muscle, based on the patient's body and preference. Researchers measured pain, arm function, quality …
Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Timing is everything: study links surgery delays to colorectal cancer survival
Knowledge-focused CompletedThis study looked at 227 people with colorectal cancer that had spread to the lining of the abdomen (peritoneal metastases). Researchers wanted to see if longer waits between chemotherapy and surgery hurt chances of survival. The goal was to find out if speeding up treatment coul…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Cancer centers unite to track COVID-19's toll on patients and staff
Knowledge-focused CompletedThis study tracked over 1,100 cancer patients and healthcare workers to understand how COVID-19 affects them. Researchers collected blood samples and health data to measure infection rates, severity, and immune responses. The goal was to learn how the virus spreads in cancer cent…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC