Institut Cancerologie De L'ouest

This study tested a chemotherapy cocktail called FOLFIRINOX in 72 patients aged 70 or older with metastatic pancreatic cancer. The doses were adjusted based on each person's genetics to reduce side effects while still fighting the tumor. The goal was to see if this approach could…

This study tested a breast reconstruction method for women who had a mastectomy, with or without radiation. Surgeons first used fat grafting to prepare the chest wall, then placed a breast implant just under the skin (not under the muscle) to reduce pain and animation. The study …

This study tested a combination of high-dose radiation and hormone therapy (leuprorelin) in 74 men with prostate cancer that had returned in up to 5 pelvic lymph nodes after initial treatment. The goal was to see if this approach could delay further cancer growth or relapse. Part…

This study tested whether a special PET scan (called 18F-DOPA PET-CT) can find brain metastases as well as or better than standard MRI in people with lung cancer, breast cancer, or melanoma. 32 adults with untreated brain metastases took part. The goal was to see if this PET meth…

This study tested a new radioactive tracer called 89Zr-TLX250 for PET scans in 12 people with metastatic triple negative breast cancer. The goal was to see if it could find more tumors than the standard FDG PET scan, especially in the brain. Researchers compared the number of les…

This early-phase study tested a new imaging agent called 89Zr-girentuximab in 6 people with non-muscle-invasive bladder cancer. The goal was to see if it could safely and clearly show tumors on PET/CT scans. Researchers looked for uptake spots in the bladder and checked for side …

This trial investigates whether a low-level diode laser can prevent or reduce severe mouth sores (mucositis) caused by radiation and chemotherapy in people with advanced head and neck cancer. Participants receive either real laser therapy or a non-functional placebo laser during …

This study tested whether giving patients non-invasive ventilation (a mask that helps them breathe) soon after surgery could prevent serious lung complications. It included 266 adults at high risk (based on a score called ARISCAT) who were having surgery under general or regional…

This study looked at whether music therapy can lower anxiety in women with early-stage breast cancer during chemotherapy. Twenty-seven patients took part, with some receiving music therapy sessions while others did not. Researchers measured anxiety levels before and after each ch…

This study tested whether a capsaicin skin patch (made from chili peppers) works better than oral pregabalin for treating nerve pain that starts soon after breast cancer surgery. 140 women who had surgery for breast cancer and developed nerve pain within 2 months were enrolled. T…

This study looked at breast reconstruction using only a patient's own fat (lipomodulin) after mastectomy for breast cancer. Researchers wanted to see how often the procedure works, how the breast looks afterward, and how it affects quality of life. The study included 118 women wh…

This study tested whether listening to audio-guided meditation during a breast biopsy helps reduce pain and anxiety. 225 women having a breast biopsy were offered meditation or standard care. Researchers measured their pain and anxiety levels before and after the procedure using …

This study looked at whether a 12-week adapted physical activity program could help cancer patients feel less tired and improve their quality of life. 37 adults with different cancer types and treatments took part. Researchers measured fatigue, quality of life, and fear of moveme…

This study tested two methods to manage blocked central venous catheters (CVCs) in 92 cancer patients before chemotherapy. One method used a chest X-ray followed by a saline injection, while the other used a contrast dye injection. The goal was to see which approach allowed docto…

This study tested whether using a virtual reality headset during cancer surgery under local anesthesia can reduce pain and anxiety. 42 adults with cancer were randomly assigned to receive either local anesthesia alone or local anesthesia plus VR. The VR used hypnosis and relaxati…

This study investigates whether having an empty bladder reduces movement of the mesorectum (tissue around the rectum) during radiotherapy for rectal cancer. About 50 adults with rectal cancer receive planning CT scans and weekly CBCT scans under both empty and full bladder condit…

This completed study included 149 healthy children aged 8 to 12 from different socioeconomic backgrounds in France. Researchers collected hair samples and questionnaires to measure chemical exposures and DNA damage. The goal was to understand how social inequalities might influen…

This study looked at whether the plastic masks used to hold the head still during brain radiotherapy affect the quality of MRI scans used for treatment planning. Three healthy volunteers had MRI scans with and without two different types of masks. The goal was to see if the masks…

This study looked at 227 people with colorectal cancer that had spread to the lining of the belly. Researchers wanted to see if waiting longer between chemotherapy and surgery affected how long patients lived without the cancer coming back. The goal is to find the best timing for…

This study looked at 27 women with breast cancer who had a mastectomy and immediate breast reconstruction with an implant. The implant was placed either above the chest muscle (prepectoral) or below it (subpectoral). Researchers measured pain, arm function, quality of life, and c…

This study aimed to understand how COVID-19 affected cancer patients and healthcare workers in cancer centers. Over 1,100 participants were followed for a year to track infections, severity, and emotional impacts. No treatments or vaccines were tested; instead, researchers collec…