Fundació Institut De Recerca De L'hospital De La Santa Creu I Sant Pau

This study is testing whether a daily dose of a common cholesterol-lowering drug, pravastatin, can help prolong pregnancy in women diagnosed with severe preeclampsia or poor fetal growth between 24 and 30 weeks. The goal is to safely delay delivery, reducing the serious health ri…

This study is testing whether a form of vitamin B3 called nicotinamide can stop or even reverse liver scarring (fibrosis) in people with fatty liver disease. About 30 overweight or obese adults will take either nicotinamide or a placebo pill daily for one year. Researchers will u…

This study is testing whether a lower dose of the heart rhythm drug amiodarone (100 mg/day) works as well as the standard dose (200 mg/day) to keep the heart in a normal rhythm after treatment for persistent atrial fibrillation. It aims to see if the lower dose can control the co…

This study aims to find out which type of device is better for holding a urinary catheter in place for patients in intensive care: an adhesive patch or an elastic band. Researchers will compare the two to see which one causes fewer skin injuries, less pain, and fewer infections. …

This study is testing if a 'fast track' recovery plan is as safe as the standard approach for children who have surgery for a burst or infected appendix. The goal is to see if kids can go home from the hospital sooner without increasing their risk of complications. Researchers wi…

This study is testing whether 3D-printed models and personalized surgical guides can help surgeons better plan and perform bone-cutting procedures (osteotomies) for Kienbock's disease, a rare condition where a small wrist bone dies from poor blood supply. The research will involv…

This study compares two surgical approaches for treating moderate to severe floating toe, where a toe doesn't touch the ground properly. Researchers want to see if a simpler bone-cutting procedure alone works as well as that same procedure combined with soft tissue repair. They'l…

This study is testing whether a medication called levetiracetam, commonly used for seizures, can prevent epileptic seizures in adults with Down syndrome who also have Alzheimer's disease. Researchers also want to see if the drug can slow down the brain changes and memory loss lin…

This study is testing a new psychological program called 'Feeling Safe' for people with schizophrenia who experience strong, distressing false beliefs (delusions). The main goal is to see if the therapy is acceptable and satisfying for participants, and if it helps improve their …

This study aims to understand the experiences of patients with a serious form of fatty liver disease (MASH) who are enrolled in a specialized care program. Researchers will interview 25 patients twice—once before they start the program and once after—to learn about their expectat…

This study aims to understand how pregnancy complications, lifestyle, and environment affect a young mother's long-term heart health. Researchers will follow 1,800 women 3-6 years after childbirth, collecting health data and lifestyle information. The goal is to develop a simple …

This study aims to understand if changes in body composition (like muscle mass) can predict how well new medications work for people with active inflammatory bowel disease (IBD). Researchers will follow 48 adults with Crohn's disease or ulcerative colitis who are starting specifi…

This study aims to understand why people with damage to specific brain areas (hypothalamus and pituitary) often have severe sleep problems. Researchers will compare 60 patients with this condition to healthy volunteers, measuring sleep patterns, hormone levels, and brain activity…

This study aims to find out how common Human Papillomavirus (HPV) infections are in the mouth and anus of men who have inflammatory bowel disease (IBD). Researchers will collect swab samples from 384 male participants and ask them to complete a questionnaire. The goal is to under…

This study aims to use artificial intelligence (AI) to analyze existing health records and glucose data from 800 adults with type 1 diabetes. The goal is to discover if there are distinct subgroups of patients who experience the disease differently. Participants will not receive …

This study aims to better understand why miscarriages happen and how to improve care for women and couples. It will enroll 225 women who have experienced a first-trimester miscarriage to investigate a wide range of possible genetic, hormonal, immune, and psychological causes. The…

This study is testing whether computer programs can learn to recognize the breathing patterns of different lung diseases like asthma and COPD. Researchers will analyze existing breathing test results from 50 adults who already have a confirmed diagnosis. The goal is to see if thi…

This study is creating and testing a new questionnaire to measure how severe a chronic cough is for patients. Researchers will enroll 100 people, including those with chronic cough and healthy volunteers, to validate the tool. The goal is to give doctors a standard way to assess …