New dialysis protocol could reduce electrolyte imbalances in ICU kidney patients

NCT ID NCT07514650

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a modified blood-thinning protocol using citrate during continuous kidney replacement therapy in 43 ICU patients with acute kidney injury. The goal is to see if the new method reduces loss of important minerals like potassium and magnesium, cutting down on the need for extra supplements. Researchers will compare the modified approach to standard dialysis techniques.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
regional citrate anticoagulation
What this could lead to
If successful, this could lead to a safer, more efficient way to perform continuous kidney replacement in critically ill patients, reducing the need for electrolyte supplements.
What could go wrong
This is a small, early-stage study (43 participants) focused on protocol validation, not a treatment. Results may not apply to all ICU patients, and the modified protocol may not show clear benefits over standard care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, Barcelona, 08041, Spain

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