Fred Hutchinson Cancer Center

This study tests a new type of COVID-19 vaccine (LUNAR-COV19) in 56 adults who have had a stem cell transplant within the past year. Standard vaccines often work less well in these patients because their immune system is weakened. The new vaccine uses a self-amplifying mRNA that …

This study is testing a smartphone app called QuitBot, along with text messaging, to help American Indian and Alaska Native adults quit smoking. About 772 participants will be randomly assigned to one of two remote programs that provide personalized support and motivation. The go…

This study compares a smartphone app (iCanQuit) alone versus the app plus nicotine replacement therapy (like patches or gum) to help Hispanic adults stop smoking. About 854 participants who smoke daily and want to quit within 30 days will be randomly assigned to one of the two gr…

This early-phase study tests a new approach for people with high-risk multiple myeloma, including those whose cancer has returned or not responded to treatment. Participants receive a radioactive antibody that seeks out and kills myeloma cells, followed by chemotherapy, radiation…

This study tests whether giving a lower dose of the immunotherapy drug nivolumab less often can still control advanced cancers that have spread or cannot be removed. About 50 adults with various cancers (like melanoma, lung, or kidney cancer) will receive the treatment. The goal …

This study compares two smartphone apps designed to help people stop smoking. One app uses a therapy that focuses on mood and behavior, while the other provides standard quitting tips. About 1,800 adults who smoke at least 5 cigarettes a day and want to quit in the next month wil…

This study tests whether using two probes during a heat-based treatment (thermal ablation) works better than the usual one-probe method to prevent cervical cancer in women living with HIV. About 200 women aged 25-49 with HIV and cervical precancer will be enrolled. The goal is to…

This study will test if using two probes during a procedure called thermal ablation works better than the usual one-probe method to prevent cervical cancer in women living with HIV. The study will involve 300 women in Rwanda who have HIV and signs of early cervical changes. The g…

This study looks at whether training pharmacy staff to better communicate about and manage the HPV vaccine can increase vaccination rates in children ages 9-17. About 1,900 participants, including pharmacy staff and parents, will be involved. The goal is to make it easier for fam…

This study looks at whether adding a remote nurse via telehealth can help more people start and continue taking HIV prevention pills (PrEP and PEP) at pharmacies in Kenya. About 1,580 pharmacy clients will take part. The goal is to see if this approach works better than the usual…

This study will test whether using two probes during thermal ablation (a heat treatment) works better than the standard one-probe method to prevent cervical cancer in women living with HIV. About 300 women in Kenya will receive the new two-probe technique, and researchers will ch…

This study tests if eating all meals within an 8-hour window each day (time-restricted eating) can reduce side effects and improve quality of life for people starting cancer treatment after surgery. Researchers will enroll 50 adults with solid tumors who are about to begin chemot…

This study tests a program called PATH that uses role-playing and therapy techniques to help cancer patients cope with spiritual and existential distress. About 20 adults with cancer will take part in six sessions. The goal is to see if the program is feasible and can improve pat…

This study tests whether an online nutrition education website can help breast cancer patients manage chemotherapy side effects like diarrhea and constipation. About 50 adults with stage I-III breast cancer will use the Cook for Your Life website alongside their usual care. The g…

This pilot study tests whether giving early-stage cancer patients a monthly cash card (no restrictions on spending) can reduce financial hardship and improve their health outcomes. Twenty newly diagnosed patients with financial concerns will receive the cards for a set period. Re…

This study looks at whether a personalized patient navigation program can help more American Indian and Alaska Native people in western Washington get screened for lung cancer. Lung cancer is a leading cause of death in these communities, but screening rates are low. The program …

This study tests a decision-making support tool designed specifically for Black individuals to help them decide whether to get screened for lung cancer. The tool uses a restorative justice approach to build trust and address historical unfairness in healthcare. Researchers will e…

This clinical trial evaluates the acceptability and effectiveness of an educational intervention (Lung Toolkit) for improving knowledge about lung cancer and lung cancer screening among American Indian/Alaskan Native (AI/AN) cigarette smokers. The Lung Toolkit is an educational i…