Charite University, Berlin, Germany
Clinical trials sponsored by Charite University, Berlin, Germany, explained in plain language.
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Could a blood filter ease chronic fatigue? new trial tests it
Disease control CompletedThis study tested whether a procedure called immunoadsorption — which filters certain antibodies out of the blood — can reduce fatigue in people with chronic fatigue syndrome (ME/CFS), including those whose condition started after COVID-19. Sixty-six adults received either five r…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Heart pouch procedure may beat blood thinners for stroke prevention
Disease control CompletedThis study tested a procedure to close a small pouch in the heart (left atrial appendage) in people with atrial fibrillation who are at high risk for both stroke and bleeding. The goal was to see if this procedure works better than standard blood-thinning medications at preventin…
Phase: PHASE4 • Sponsor: Charite University, Berlin, Germany • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Which cream wins? study tests two skin protectants against diaper rash in seniors
Prevention CompletedThis study tested two different skin protection products to prevent incontinence-associated dermatitis (a type of diaper rash) in elderly nursing home residents. Researchers compared a film-forming protectant and a lipophilic (oil-based) protectant against no treatment in 220 par…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Prevention
Last updated Jun 27, 2026 11:02 UTC
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Can a smartphone help silence distressing voices? online self-help program tested for psychosis
Symptom relief CompletedThis study tests whether a 6-week online self-help program can help people with psychotic disorders who hear voices at least once a week. The program combines metacognitive training and mindfulness techniques to reduce the frequency and distress of auditory hallucinations. Partic…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Symptom relief
Last updated Jul 02, 2026 02:00 UTC
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New device aims to get ICU patients standing sooner
Symptom relief CompletedThis pilot study tested a device called Liana that helps critically ill patients on breathing machines sit up and stand. The goal was to see if using the device allows patients to reach a higher level of mobility (like standing) more often during their ICU stay. Forty adult patie…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can the 'Love Hormone' help schizophrenia patients connect better?
Symptom relief CompletedThis study tested whether giving oxytocin nasal spray before mindfulness-based group therapy could reduce negative symptoms (like lack of motivation or social withdrawal) in people with schizophrenia. 42 participants were randomly assigned to receive either oxytocin or a placebo …
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Immune system clues may predict infections in ICU patients
Knowledge-focused CompletedThis completed study looked at 686 patients with acute respiratory distress syndrome (ARDS) to see how their immune status affects the risk of secondary infections like herpes or cytomegalovirus. Researchers measured immune cells and virus reactivation in blood and lung samples. …
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Can a web app spot brain fog years later? study tests home-based cognitive checkups
Knowledge-focused CompletedThis study followed 76 people from an earlier study (BioCog) to see if their thinking and memory skills changed 7 to 10 years later. Participants took cognitive tests through a web application at home, plus a phone or video visit. The goal was to see if remote testing can reliabl…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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AI helps kidney patients discuss future treatment options
Knowledge-focused CompletedThis study tested whether an AI tool that predicts the risk of kidney transplant failure within one year can improve conversations between patients, their families, and doctors. 76 adults with a functioning kidney transplant but declining kidney function took part. The goal was t…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Ventilator settings may impact heart function in kids with heart defects
Knowledge-focused CompletedThis study looked at how different levels of ventilator pressure (PEEP) affect the heart's ability to pump blood in children under 5 with congenital heart disease who are on breathing machines. Researchers measured changes in cardiac output and right heart function in 58 children…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Oxygen therapy under the microscope for chronic fatigue
Knowledge-focused CompletedThis study watched 60 adults with ME/CFS (a condition causing severe fatigue) after they received hyperbaric oxygen therapy (HBOT) in a high-pressure chamber. Participants filled out health questionnaires to track changes in physical function and fatigue. The goal was not to prov…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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AI Doctor's helper: ChatGPT checks COPD care
Knowledge-focused CompletedThis study tested whether a large language model (like GPT-4) could help doctors follow official treatment guidelines for COPD. 78 hospitalized COPD patients were randomly assigned to either receive standard care or have their discharge treatment reviewed by the AI. The goal was …
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:04 UTC
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10-Year Follow-Up reveals best way to image heart arteries
Knowledge-focused CompletedThis study followed 318 people with suspected coronary artery disease for about 10 years to see whether starting with a CT scan or an invasive angiogram leads to better long-term outcomes. Participants had already completed an earlier study and agreed to additional follow-up, inc…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Skin fluid may reveal heart failure secrets without needles
Knowledge-focused CompletedThis study looked at whether signs of heart failure can be found in fluid just under the skin, called dermal interstitial fluid. Researchers tested 20 heart failure patients using a special device to collect this fluid during exercise. The goal was to see if these skin-based mark…
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Pasteurizing breastmilk: help or hindrance for tiny babies?
Knowledge-focused CompletedThis study reviewed medical records of 900 very low birth weight preterm infants to compare outcomes between those fed raw (unpasteurized) mother's milk and those fed pasteurized mother's milk. The researchers also looked at whether the baby's sex played a role. The goal is to un…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Can virtual reality help fight alcohol addiction?
Knowledge-focused CompletedThis study looked at whether a strong sense of 'presence' during virtual reality therapy could help people with alcohol dependence manage cravings and avoid relapse. Sixty abstinent patients who had recently completed withdrawal treatment took part. Researchers measured craving l…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Could a simple breath stop fever seizures? new study investigates
Knowledge-focused CompletedThis study looked at 100 children with fever to see if those who have febrile seizures breathe differently. Researchers measured breathing rate, carbon dioxide levels, and body temperature while children slept. The goal is to understand why some children have seizures during feve…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC