Ventilator settings may impact heart function in kids with heart defects

NCT ID NCT06270485

Completed Knowledge-focused Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how different levels of ventilator pressure (PEEP) affect the heart's ability to pump blood in children under 5 with congenital heart disease who are on breathing machines. Researchers measured changes in cardiac output and right heart function in 58 children. The goal is to find safer ventilator settings for this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose safer ventilator settings for young children with heart conditions.
What could go wrong: This is a small, completed trial with only 58 children. Results may not apply to all children or settings, and no direct treatment benefit was tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILDREN, ONLY CONGENITAL HEART DISEASE HEMODYNAMIC INSTABILITY VENTILATION THERAPY; COMPLICATIONS

Ventilator settings may impact heart function in kids with heart defects

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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