Ventilator settings may impact heart function in kids with heart defects
NCT ID NCT06270485
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how different levels of ventilator pressure (PEEP) affect the heart's ability to pump blood in children under 5 with congenital heart disease who are on breathing machines. Researchers measured changes in cardiac output and right heart function in 58 children. The goal is to find safer ventilator settings for this vulnerable group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors choose safer ventilator settings for young children with heart conditions.
What could go wrong
This is a small, completed trial with only 58 children. Results may not apply to all children or settings, and no direct treatment benefit was tested.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Deutsches Herzzentrum der Charité
Berlin, State of Berlin, 13353, Germany
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UMCG
Groningen, Netherlands