CHILDREN, ONLY

This study is testing whether a continuous blood filtering treatment helps children with severe bloodstream infections (sepsis) survive and recover better than standard care. Researchers will compare two groups of children to see if early use of this blood purification improves 2…

This study is testing whether a drug called infliximab works better alone or when combined with other immunosuppressive medications to control Crohn's disease in children. It will involve 128 children aged 6-18 who have active Crohn's disease. The main goal is to see which approa…

This study is testing whether a specially designed online game can help children with type 1 diabetes. Researchers will see if playing the game for 9 weeks improves blood sugar control, confidence in managing the condition, and overall quality of life. The study involves 58 child…

This study aims to find out which type of exercise is better for improving heart and lung fitness in children: regular aerobic exercise or low-intensity interval training. It will involve 130 healthy school children aged 6-12 who will follow an 8-week exercise program. The goal i…

This study is testing if sniffing a pad soaked in rubbing alcohol (isopropyl alcohol) can safely reduce nausea and vomiting in children visiting the emergency room. It will compare the sniffing method against a standard nausea medication (ondansetron) and a placebo (a saline wipe…

This study is testing whether adding mat Pilates exercises to standard physical therapy helps school children (ages 8-16) who have poor posture and pain in their neck, shoulders, and back. Researchers will compare two groups: one doing Pilates plus therapy, and one doing therapy …

This study is observing what types of pneumonia-causing bacteria live in children's noses, comparing kids with ear infections to healthy children. Researchers want to understand if childhood vaccines have changed which bacteria strains are present and how resistant they are to an…

This study follows 300 critically ill children who survived sepsis for five years after leaving the hospital. Researchers want to understand how sepsis affects long-term growth, brain development, survival rates, and quality of life. The study compares these children to similar c…

This study aims to better understand how common and impactful Respiratory Syncytial Virus (RSV) infections and related ear infections are in children under 2 years old. Researchers will follow nearly 2,000 children for up to 5 years to track their health visits, treatments, and h…

This study is testing whether it's possible to measure and improve sleep for children aged 3-6 who are critically ill in intensive care. Researchers will use wrist monitors and saliva tests to track sleep patterns while trying two simple interventions: providing normal daytime li…