CHILDREN, ONLY

This study tests whether combining task-oriented training with functional electrical stimulation (FES) can improve balance and ankle strength in children aged 6-9 with hemiparesis (weakness on one side). Thirty-six children will participate in a structured exercise program three …

This study compares two treatments for children aged 6-18 with Crohn's disease: one group gets infliximab alone, another gets immunosuppressives alone, and a third gets both. The goal is to see which approach leads to more kids achieving remission (feeling better and showing heal…

This study looks at whether continuous blood purification (a slow, steady filtering of the blood) works better than standard non-continuous methods for children with severe sepsis. Researchers will track survival rates and kidney function in 90 children aged 29 days to 18 years. …

This study is testing whether a specially designed digital game can help children aged 8-13 with type 1 diabetes improve their blood sugar control, confidence in managing their diabetes, and overall quality of life. The game is based on a health education model and will be played…

This study tests whether a virtual reality (VR) simulation of an MRI scan can help children aged 4-18 stay calm enough to complete the real scan without anesthesia. About 288 children will be randomly assigned to VR preparation, a booklet, or usual care. The main goal is to see i…

This study looks at whether mat Pilates, combined with routine physical therapy, can reduce pain and improve posture in school-aged children (8–16 years) with Upper Crossed Syndrome—a condition marked by forward head, rounded shoulders, and a curved upper back. Half of the 28 par…

This study tests whether inhaling isopropyl alcohol (rubbing alcohol) can reduce nausea in children aged 7 to 17 in the emergency department. About 84 kids will be randomly assigned to sniff an alcohol pad, a standard nausea medicine (ondansetron), or a placebo (saline pad). The …

This study looks at whether using a squat toilet versus a sitting toilet affects ankle flexibility, leg strength, and constipation in school children aged 6 to 12. Researchers will measure ankle range of motion, leg power, and constipation symptoms in 191 kids from public and pri…

This study is a national observatory that will follow 10,000 children and newborns with bacterial meningitis. Researchers aim to understand which bacteria are causing infections, how often treatments fail, and how well vaccines are working. The goal is to improve future treatment…

This study tests whether it is possible to measure and improve sleep and body clock rhythms in children aged 3 to 6 who are in the pediatric intensive care unit (PICU). Researchers will use a watch-like device and saliva tests to track sleep, and try two simple approaches: bright…

This study looks at how often young children get ear infections from RSV, a common virus. Researchers will track 1900 children under 2 years old to see how many have RSV-related ear infections, with or without bronchiolitis. The goal is to better understand the burden of RSV in t…

This large observational study is checking how pneumococcal vaccines have changed the types of bacteria living in children's noses. Researchers will compare healthy children and those with ear infections to see which bacterial strains are present and whether they resist antibioti…

This study looks at how different types of exercise affect heart and lung fitness in healthy school children aged 6 to 12. Researchers will compare aerobic exercises (like running) with low-intensity interval training (short bursts of activity with rest). The goal is to find whic…

This study follows 300 critically ill children with sepsis for five years after they leave the hospital. Researchers want to see how sepsis affects their growth, brain development, survival, and quality of life. The goal is to better understand the long-term challenges these chil…