Centre Francois Baclesse

This study is testing whether a digital app that lets patients report their symptoms weekly helps doctors better manage side effects for people taking two cancer drugs (cabozantinib and nivolumab) for advanced kidney cancer. It involves 83 adults who are starting this specific dr…

This study is testing whether doctors can safely avoid radiating the healthy tissue flap used to reconstruct the mouth after oral cancer surgery. The goal is to reduce side effects like pain and difficulty swallowing while still keeping the cancer from coming back. About 348 pati…

This study is testing a new way to help women after finishing initial treatment for ovarian or endometrial cancer. It compares a personalized support plan that includes a team assessment in a day hospital to a standard plan without that extra step. The goal is to see if the more …

This study is testing a strategy to help patients whose kidney cancer has started to spread to just a few new spots while their current medications are still controlling the rest. The goal is to use very precise, high-dose radiation to destroy these few new spots. Researchers hop…

This study is testing whether a special web application can help breast cancer patients better follow their prescribed hormone therapy after initial treatment. Researchers will compare patients using the app to those receiving standard care to see if it improves how consistently …

This study aims to find the best way to use highly focused radiation to control a small number of tumors that have spread to the brain from other cancers. It will compare a single high-dose treatment to a newer approach using three smaller doses, to see which is better at destroy…

This trial is testing whether a two-drug combination (talazoparib and avelumab) can help keep advanced bladder cancer from getting worse after initial chemotherapy. It will involve 50 patients whose cancer responded to or was stable after platinum-based chemo. The goal is to see …

This large trial is comparing two approaches for patients with intermediate-risk thyroid cancer after surgery. One group receives standard radioactive iodine treatment. The other group only gets this treatment if specific blood tests and scans suggest it's needed. The goal is to …

This study is comparing two different lab tests to see which one better identifies ovarian cancer patients who are likely to respond well to chemotherapy and may benefit from a follow-up targeted drug. It involves 88 women newly diagnosed with advanced ovarian cancer. The goal is…

This study is testing whether a small device that gently stimulates a nerve in the ear can improve quality of life for women undergoing first-line chemotherapy for ovarian cancer. The device aims to reduce digestive symptoms like nausea and discomfort that often come with treatme…

This study is testing whether personalized beauty and skincare services can help people with head and neck cancer feel better about their appearance during treatment. It will involve 55 adult patients who are starting cancer treatment. The main goal is to see if this supportive c…

This study is testing whether using a special walking platform every day helps older adults (age 65+) recover their normal walking speed after cancer surgery. Researchers will compare patients who use the platform to those who receive standard care. The main goal is to see if mor…

This study compares two scalp cooling techniques to prevent hair loss in women receiving chemotherapy for early-stage breast cancer. Researchers will test both a traditional cooling cap and a newer cooling mask to see which works better at preserving hair. They'll also measure ho…

This study is testing if an online brain exercise program works better when a trained coach supervises it remotely. It's for people with breast cancer who have finished chemotherapy and are struggling with memory and thinking problems, often called 'chemo fog.' Researchers want t…

This study aims to create 3D models called 'tumor organoids' from cancer tissue samples of patients with undifferentiated carcinoma. Researchers will grow these mini-tumors in the lab and test different treatments on them to see which might work best for each patient. The goal is…

This study aims to collect tumor samples from people with triple-negative breast cancer to grow them into 3D models called organoids in the lab. Researchers will use these 'mini-tumors' to test how well new, innovative therapies might work and to search for biological markers tha…

This study aims to understand how common sleep problems affect memory, thinking skills, and overall well-being in people being treated for breast cancer. Researchers will observe 75 patients, using sleep trackers and questionnaires to measure sleep patterns and cognitive function…

This study aims to understand the long-term impact on thinking skills and daily function for people with a specific brain tumor (cavernous sinus meningioma) treated with radiation. It will compare two modern radiation techniques—proton therapy and standard photon therapy—to see i…