Brain training with a virtual coach may fight chemo fog

NCT ID NCT06027632

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether online cognitive exercises, guided by a neuropsychologist, can reduce memory and thinking problems (chemo brain) in 300 breast cancer patients after chemotherapy. Participants will do 20-minute brain games three times a week for 12 weeks, with some getting weekly video coaching. The goal is to see if the coaching helps more than doing the exercises alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
computerized cognitive stimulation program (HAPPYneuron-Pro)
What this could lead to
If it works, this could offer a practical, at-home way to reduce 'chemo brain' and improve daily thinking skills for breast cancer survivors.
What could go wrong
This is an early-stage study with no prior results for this specific supervised approach. The benefit may be small or no better than unsupervised exercises, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH Métropole Savoie

    RECRUITING

    Chambéry, France

  • CHU de Limoges

    RECRUITING

    Limoges, France

  • CHU de Nimes

    RECRUITING

    Nîmes, France

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

  • Centre Arrmoricain d'Oncologie

    NOT_YET_RECRUITING

    Plérin, France

  • Centre Eugène Marquis

    RECRUITING

    Rennes, France

  • Centre François Baclesse

    RECRUITING

    Caen, 14000, France

  • Centre George François Leclerc

    NOT_YET_RECRUITING

    Dijon, France

  • Centre Henri Becquerel

    RECRUITING

    Rouen, France

  • Centre Jean Perrin

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

  • Centre hospitalier de Bligny

    RECRUITING

    Briis-sous-Forges, France

  • Centre hospitalier de Pau

    RECRUITING

    Pau, France

  • Clinique Haute Energie

    NOT_YET_RECRUITING

    Nice, France

  • Clinique Mathilde

    RECRUITING

    Rouen, France

  • Clinique Medico-chirurgicale Charcot

    NOT_YET_RECRUITING

    Sainte-Foy-lès-Lyon, France

  • Groupe Hospitalier Mutualiste de Grenoble

    RECRUITING

    Grenoble, France

  • Gustave Roussy

    RECRUITING

    Villejuif, France

  • Hôpital Saint-Louis

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital privé du Confluent

    RECRUITING

    Nantes, France

  • ICM Val d'Aurelle

    RECRUITING

    Montpellier, France

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

  • Institut de Cancérologie de Lorraine

    NOT_YET_RECRUITING

    Nancy, France

  • La Pitié Salpétrière

    NOT_YET_RECRUITING

    Paris, France

  • Polyclinique Bordeaux Nord Aquitaine

    NOT_YET_RECRUITING

    Bordeaux, France

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