Brain training with a virtual coach may fight chemo fog

NCT ID NCT06027632

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether online cognitive exercises, guided by a neuropsychologist, can reduce memory and thinking problems (chemo brain) in 300 breast cancer patients after chemotherapy. Participants will do 20-minute brain games three times a week for 12 weeks, with some getting weekly video coaching. The goal is to see if the coaching helps more than doing the exercises alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

computerized cognitive stimulation program (HAPPYneuron-Pro)

What this could lead to

If it works, this could offer a practical, at-home way to reduce 'chemo brain' and improve daily thinking skills for breast cancer survivors.

What could go wrong

This is an early-stage study with no prior results for this specific supervised approach. The benefit may be small or no better than unsupervised exercises, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cognitive disorder Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH Métropole Savoie

    RECRUITING

    Chambéry, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Limoges

    RECRUITING

    Limoges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Nimes

    RECRUITING

    Nîmes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Centre Arrmoricain d'Oncologie

    NOT_YET_RECRUITING

    Plérin, France

    Contact

    Contact

  • Centre Eugène Marquis

    RECRUITING

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre François Baclesse

    RECRUITING

    Caen, 14000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre George François Leclerc

    NOT_YET_RECRUITING

    Dijon, France

    Contact

    Contact

  • Centre Henri Becquerel

    RECRUITING

    Rouen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Jean Perrin

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

    Contact

    Contact

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre hospitalier de Bligny

    RECRUITING

    Briis-sous-Forges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre hospitalier de Pau

    RECRUITING

    Pau, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Clinique Haute Energie

    NOT_YET_RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Clinique Mathilde

    RECRUITING

    Rouen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Clinique Medico-chirurgicale Charcot

    NOT_YET_RECRUITING

    Sainte-Foy-lès-Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Groupe Hospitalier Mutualiste de Grenoble

    RECRUITING

    Grenoble, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Gustave Roussy

    RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Hôpital Saint-Louis

    NOT_YET_RECRUITING

    Paris, France

    Contact

    Contact

  • Hôpital privé du Confluent

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • ICM Val d'Aurelle

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de Cancérologie de Lorraine

    NOT_YET_RECRUITING

    Nancy, France

    Contact

    Contact

  • La Pitié Salpétrière

    NOT_YET_RECRUITING

    Paris, France

    Contact

    Contact

  • Polyclinique Bordeaux Nord Aquitaine

    NOT_YET_RECRUITING

    Bordeaux, France

    Contact

    Contact