Centre Francois Baclesse

This study aimed to test a new treatment for people whose cancer came back after earlier radiation therapy. The approach combined special nanoparticles injected into the blood with targeted proton therapy to try to control the tumor. The study was withdrawn before any participant…

This study tests whether adding the drug olaparib to standard radiation and chemotherapy can help people with aggressive, inoperable brain tumors live longer. About 91 participants will receive the combination treatment. The goal is to find the best dose and see if it improves su…

This study tests a precise radiation method (SIB-IMRT) combined with chemotherapy for people with locally advanced anal cancer. The goal is to see if this approach can reduce severe side effects and avoid treatment pauses, while still controlling the cancer. About 71 adults with …

This study looks at how to better support women who have finished treatment for ovarian or endometrial cancer. Researchers will assess patients' needs for supportive care and create a personalized plan to help manage long-term side effects. The goal is to improve quality of life …

This study aims to understand head and neck cancers that occur during pregnancy or within a year after giving birth. Researchers will look at virus exposure (HPV and EBV), pregnancy complications, and tumor types in about 14 women. The goal is to gather information, not to test a…

This study looks at whether adding a weekly check by a specially trained medical technician (called a MERM) to the usual doctor visits can improve how we spot side effects in people getting proton therapy for brain or head-and-neck tumors. About 92 adults will be randomly assigne…

This study looks at women who have recovered from rare ovarian cancers (germ cell or sex cord-stromal tumors) to understand how chemotherapy affects their energy, heart and lung health, and overall quality of life. About 268 participants will fill out questionnaires and undergo t…