New hope for incurable brain cancer: drug combo shows promise

NCT ID NCT03212742

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 36 times

Summary

This study tests whether adding the drug olaparib to standard radiation and chemotherapy can help people with aggressive, inoperable brain tumors live longer. About 91 participants will receive the combination treatment. The goal is to find the best dose and see if it improves survival at 12 months.

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Contacts and locations

Locations

  • CH du Havre

    Le Havre, France

  • CHU

    Amiens, France

  • CHU

    Bordeaux, France

  • Centre Eugène Marquis

    Rennes, France

  • Centre François Baclesse

    Caen, 14076, France

  • Centre Guillaume le Conquérant

    Le Havre, France

  • Centre Henri Becquerel

    Rouen, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, France

  • Centre léon Bérard

    Lyon, France

  • GHBS

    Lorient, France

  • Hôpitaux universitaires La Pitié Salpétrière - Charles Foix

    Paris, France

  • Institut Claudius Regaud

    Toulouse, France

  • Institut Curie

    Paris, France

  • Institut de Cancérologie de l'Ouest

    Angers, France

  • Institut de Cancérologie de l'Ouest

    Saint-Herblain, France

Conditions

Explore the condition pages connected to this study.