Cold war on baldness: which scalp cooling method wins for breast cancer patients?

NCT ID NCT06011525

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two ways to cool the scalp during chemotherapy to prevent hair loss in women with localized breast cancer. One uses a standard cold cap with a compression bandage, the other a cooling mask. Researchers will compare how well each prevents hair loss, and also look at quality of life, self-image, and costs. The goal is to find which technique works best and is most worth using.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
scalp cooling device (cold cap or cooling mask)
What this could lead to
If successful, this could provide a better, more effective way to prevent chemotherapy-induced hair loss, improving quality of life for breast cancer patients.
What could go wrong
This is a moderate-sized trial (196 participants) comparing two existing techniques, not a new breakthrough. Results may show only modest differences, and effectiveness varies by individual.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Oscar Lambret

    Lille, France

  • IUCT-Oncopole

    Toulouse, France

  • centre François Baclesse

    Caen, 14000, France

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