New radiation approach aims to spare healthy tissue in sinus cancer treatment

NCT ID NCT05943119

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests a new way to give radiation for sinus cancer after endoscopic surgery. Instead of radiating the whole sinus area, doctors will use a 'dose painting' technique that targets only the areas where cancer was found. The goal is to see if this reduces side effects like damage to the nose, eyes, ears, and brain. About 52 adults with sinus tumors will be randomly assigned to either the new targeted radiation or standard full-sinus radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiotherapy (dose-painting radiation)

What this could lead to

If successful, this approach could reduce severe side effects from radiation while still controlling sinus cancer.

What could go wrong

This is a small, early-phase trial (52 people). It may not show a clear benefit, and the targeted method might miss some cancer cells.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Fistula neoplasm paranasal sinus cancer paranasal sinus carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU CAEN

    NOT_YET_RECRUITING

    Caen, France

    Contact

  • Centre Francois Baclesse

    RECRUITING

    Caen, France

    Contact

  • Centre Oscar Lambret

    NOT_YET_RECRUITING

    Lille, France

    Contact