Zapping cancer spots could delay stronger drugs
NCT ID NCT04299646
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether high-dose, precise radiation (stereotactic radiotherapy) can control a few growing kidney cancer spots while the rest of the disease is stable on current medication. About 77 people with metastatic kidney cancer whose tumors are progressing in only a few places will receive radiation to those spots. The goal is to see if this can delay the need to switch to a new, often stronger, systemic therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
stereotactic radiotherapy
What this could lead to
If it works, this approach could help people with kidney cancer stay on their current treatment longer and delay switching to harsher drugs.
What could go wrong
This is a small, early-phase study with only 77 participants. It may not prove effective, and radiation can cause side effects like fatigue or local tissue damage.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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CHD Vendée
NOT_YET_RECRUITINGLa Roche-sur-Yon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHR
NOT_YET_RECRUITINGMetz, France
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CHU Henri Mondor
NOT_YET_RECRUITINGCréteil, France
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CHU La Timone
NOT_YET_RECRUITINGMarseille, France
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Centre Antoine Lacassagne
NOT_YET_RECRUITINGNice, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre François Baclesse
RECRUITINGCaen, 14076, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Georges François LECLERC
NOT_YET_RECRUITINGDijon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Haute Energie
NOT_YET_RECRUITINGNice, France
Contact Email: •••••@•••••
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Centre Henri Becquerel
NOT_YET_RECRUITINGRouen, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Hospitalier Annecy Genevois
NOT_YET_RECRUITINGPringy, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Jean Perrin
NOT_YET_RECRUITINGClermont-Ferrand, France
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Centre Léon Bérard
NOT_YET_RECRUITINGLyon, France
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Centre Oscar Lambret
RECRUITINGLille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre de radiothérapie Guillaume le Conquérant
NOT_YET_RECRUITINGLe Havre, France
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Centre marie Curie
RECRUITINGValence, France
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Clinique Claude Bernard
NOT_YET_RECRUITINGAlbi, France
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Groupement de radiothérapie Oncologie des Pyrénées
NOT_YET_RECRUITINGPau, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ICM
NOT_YET_RECRUITINGMontpellier, France
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IUCT
NOT_YET_RECRUITINGToulouse, France
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Institut Bergonié
NOT_YET_RECRUITINGBordeaux, France
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Institut Curie
NOT_YET_RECRUITINGParis, France
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Institut Gustave Roussy
RECRUITINGVillejuif, France
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Institut Paoli Calmette
NOT_YET_RECRUITINGMarseille, France
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Institut de Cancérologie de Lorraine
NOT_YET_RECRUITINGNancy, France
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Institut de Cancérologie de l'Ouest
RECRUITINGAngers, France
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Institut de Cancérologie de l'Ouest
RECRUITINGNantes, France
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Institut de Cancérologie de la Loire Lucien Neuwirth
NOT_YET_RECRUITINGSaint-Etienne, France
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Institut de cancérologie de Bourgogne (Dijon, Auxerre, Chalon sur Saône)
RECRUITINGDijon, France
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Polyclinique de l'Ormeau
RECRUITINGTarbes, France
Contact Email: •••••@•••••
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Radiothérapie Bordeaux Nord Aquitaine
NOT_YET_RECRUITINGBordeaux, France
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Contact