Case Comprehensive Cancer Center

This early-stage study is testing whether adding an experimental drug called ruxolitinib to standard brain cancer treatment (radiation and chemotherapy) is safe for patients. Researchers want to find the highest dose of ruxolitinib that patients can tolerate without severe side e…

This early-stage study is testing whether adding the drug ivosidenib to standard chemotherapy (mFOLFIRINOX) before surgery helps people with operable pancreatic cancer. The goal is to see if this combination is safe and effective at shrinking tumors before surgical removal. Resea…

This study is testing a two-part treatment for adults whose aggressive brain cancer (glioblastoma) has returned. First, surgeons use a laser to precisely heat and destroy the tumor. Then, patients receive an immunotherapy drug (pembrolizumab) designed to help their own immune sys…

This study aimed to test a new three-drug combination for advanced liver cancer that cannot be removed by surgery. It planned to add an experimental drug called BC3402 to a standard two-drug immunotherapy regimen to see if it was safe and more effective. The trial was withdrawn b…

This early study is testing whether adding tiny radioactive pellets directly into tumors can boost the effectiveness of standard immunotherapy drugs. The trial involves just 5 patients with advanced melanoma, kidney cancer, or bladder cancer that has spread. Researchers want to s…

This study is testing an oral medication called Abemaciclib for people with certain aggressive lung cancers that have either not responded to standard chemotherapy or have come back after treatment. The goal is to see if the drug can shrink tumors and control the cancer's growth …

This early-stage study is testing whether adding the drug ibrutinib to standard radiation and chemotherapy (temozolomide) is safe for people newly diagnosed with glioblastoma, an aggressive brain cancer. Researchers want to find the highest safe dose of ibrutinib and see if radia…

This study is testing a new type of MRI scan called magnetic resonance fingerprinting (MRF) to see if it can improve how doctors diagnose and monitor brain tumors. Researchers will compare the detailed pictures from this new scan with standard scans, biopsy results, and patient o…

This study is developing and testing a shorter version of mindfulness therapy specifically for older Black women who have survived breast cancer and are experiencing mild to moderate depression. The program involves 8 weekly one-hour online group sessions that combine mindfulness…

This study aims to understand the genetic causes of several rare blood diseases by analyzing patients' DNA. Researchers will look for specific genetic changes that might be targeted by existing or future treatments. The study involves collecting blood or tissue samples from 135 p…

This study aimed to understand how much information people can remember about their own cancer screening and diagnosis. Researchers wanted to see if giving people time or helping them access their online medical records would help them recall more accurate details. The study was …

This study aimed to create and test a better training program for family members who care for head and neck cancer patients with a tracheostomy (a breathing tube in the neck). It planned to measure if the training made caregivers feel more confident and prepared, and if it led to…

This study aims to understand the unique experiences and decision-making challenges faced by Spanish-speaking Latiné men after prostate cancer treatment. Researchers will conduct focus groups with survivors to learn about their cultural perspectives and needs regarding health iss…

This study is testing whether a personalized approach can help guide treatment for adults with advanced cancers that have returned or stopped responding to standard treatments. Researchers will test cancer cells from 36 participants in a lab to see which drugs they respond to, th…