Case Comprehensive Cancer Center

This early-phase trial tests whether adding the drug ibrutinib to standard radiation and chemotherapy is safe for people with a newly diagnosed aggressive brain cancer called glioblastoma. The study includes 36 participants and looks at different doses based on a specific genetic…

This early-phase trial tests whether adding the targeted drug ivosidenib to standard chemotherapy can help shrink pancreatic tumors before surgery. About 16 people with resectable pancreatic cancer will take part. The main goal is to find the safest dose and see how well the comb…

This study planned to test whether surgeons could safely operate a robot from far away to treat prostate cancer. It was designed for adults needing robotic prostate surgery. However, the trial was withdrawn before any patients joined, so no results are available.

This study aimed to test a new experimental drug called BC3402 combined with two other drugs (tremelimumab and durvalumab) for people with advanced liver cancer that cannot be removed by surgery. The goal was to see if the combination could shrink tumors and improve survival. How…

This early-phase study tests whether adding the experimental drug ruxolitinib to standard brain cancer treatment (radiation and temozolomide) is safe and tolerable for people with newly diagnosed aggressive brain tumors called grade III gliomas or glioblastoma. The study involves…

This early-phase study tested whether adding a low-dose internal radiation implant (brachytherapy) to standard immunotherapy could help shrink tumors in people with advanced melanoma, kidney cancer, or urinary tract cancer. Only 5 participants were enrolled, and the main goal was…

This study tests a pill called abemaciclib in people with specific lung cancers (small cell, large cell neuroendocrine, and related types) that have stopped responding to chemotherapy. The goal is to see if the drug can shrink tumors and how safe it is. 14 participants will recei…

This study tests a new approach for adults with recurrent glioblastoma, an aggressive brain cancer. It combines a minimally invasive laser that heats and destroys tumor tissue (LITT) with pembrolizumab, an immunotherapy drug that helps the immune system fight cancer. The goal is …

This study tests a new MRI technique called magnetic resonance fingerprinting (MRF) to see if it can improve how doctors diagnose and assess brain tumors. About 172 people with brain tumors will get an MRF scan, and the results will be compared with standard tests and biopsy resu…

This study aims to create and test a shortened mindfulness program to help older African American women who have had breast cancer feel less depressed. About 23 women aged 65 and older with mild to moderate depression will take part. The goal is to see if the program is practical…

This study looks at whether adding a personalized exercise program to standard radiation therapy can improve quality of life and physical function in men with metastatic prostate cancer. About 80 participants will either receive exercise therapy or not, and researchers will track…

This study explores whether personalized treatment recommendations based on lab tests of a patient's own tumor can be made within 4 weeks for adults with relapsed or refractory cancers who have no standard curative options. Researchers will use drug sensitivity testing and geneti…

This study aimed to develop a standardized teaching program to help caregivers feel confident managing a loved one's tracheostomy after head and neck cancer surgery. It planned to enroll patients and their family caregivers, but the study was withdrawn before any participants wer…

This study tests a fast, motion-resistant brain MRI technique called Magnetic Resonance Fingerprinting (MRF) in children, teens, and young adults with acute leukemia. The goal is to see if the scan can detect brain changes caused by chemotherapy drugs that enter the brain. Partic…

This study looks at the DNA of people with rare blood diseases like Castleman disease and histiocytosis. The goal is to find genetic changes that could be targeted with existing or new treatments. About 135 participants will provide samples for genetic testing. The study is curre…

This study was designed to learn how much information people can recall about their own cancer screening and diagnosis. Researchers planned to see if giving extra time or resources helps people remember more accurately. The study was withdrawn before enrolling any participants, s…

This study explores whether an Apple Watch can detect changes in walking, heart rate, breathing, and sleep in people with glioblastoma (a type of brain cancer). The goal is to see if these measurements can predict symptom changes or complications before they happen. About 25 adul…

This study looks at how Spanish-speaking Latiné men who have had prostate cancer surgery make decisions about their health after treatment. Researchers will talk to 55 people in focus groups to understand their unique cultural and language needs. The goal is to create better educ…