Case Comprehensive Cancer Center

This study is testing whether transplanting intestines and other abdominal organs can help people with a rare, advanced abdominal cancer called pseudomyxoma peritonei when other treatments aren't possible. Twenty patients who cannot have their tumors surgically removed will recei…

This study is testing if freezing a tumor with liquid nitrogen before starting standard chemotherapy helps people with locally advanced esophageal cancer. Researchers want to see if this two-step approach leads to a better response and helps the body's immune system fight the can…

This study aims to see if special MRI scans taken before surgery can predict whether surgeons will be able to remove all tonsil cancer with clean margins. Researchers will enroll 30 adults with HPV-positive tonsil cancer who are scheduled for robotic surgery. The goal is to help …

This study is testing if a special microsurgery, called lymphaticovenous bypass (LVB), can prevent a painful and chronic side effect called lymphedema. Lymphedema is arm swelling that affects up to 40% of people after breast cancer surgery to remove lymph nodes. The trial will co…

This study is for people whose cancer has spread to the brain. It compares two ways of delivering whole brain radiation therapy, both designed to protect thinking and memory. One method avoids the hippocampus, a key memory area. The other avoids the hippocampus plus several other…

This study is testing a new, brief mindfulness program delivered by daily text messages to help reduce symptoms of depression in people who have recently finished treatment for early-stage breast, prostate, or colorectal cancer. Researchers want to see if this short, daily format…

This study is testing a new, faster process for delivering targeted radiation to relieve severe abdominal pain caused by pancreatic cancer. Instead of scheduling a new scan and waiting over a week for a treatment plan, doctors will use a patient's existing diagnostic scan to plan…

This study is testing if a natural product made from freeze-dried miracle fruit can help people who are having taste problems from their cancer treatment. About 45 adults with solid tumor cancers will take the berry product up to four times a day before meals for 90 days. Researc…

This small pilot study aims to see if a larger trial is feasible to test a daily irrigation procedure for people suffering from severe bowel problems after rectal cancer surgery. The procedure, called transanal irrigation, involves using water to help empty the bowel on a schedul…

This study aims to see if taking a probiotic supplement changes the community of bacteria and fungi in the gut and breast tissue of people with breast cancer. Researchers will compare 100 participants, with half taking the probiotic and half taking a placebo, to measure changes i…

This study aims to understand why cancer survivors face higher risks for conditions like diabetes and heart disease later in life. Researchers will compare blood levels of specific proteins and aging markers between 120 cancer survivors and people who never had cancer. The goal i…

This study aims to understand how a light-based treatment, with or without Vitamin D, affects the immune system's response to common skin cancers. Researchers will study adults in Ohio who are already scheduled for skin cancer surgery. Participants may take Vitamin D or a placebo…