Case Comprehensive Cancer Center

This study tests whether an intestinal or multivisceral transplant can help people with a rare abdominal cancer called pseudomyxoma peritonei (PMP) that cannot be removed by surgery. Twenty participants will receive the transplant and be followed for 12 months to see if they surv…

This study tests an experimental drug called elranatamab in people newly diagnosed with AL amyloidosis who have not yet had treatment. The drug helps the body's immune cells find and destroy the abnormal cells causing the disease. Researchers want to see if it can produce deep re…

This phase 1 trial tests whether disulfiram, a drug long used for alcohol dependence, can reduce immune suppression caused by high-grade gliomas. Participants take disulfiram for 3 to 14 days before their scheduled tumor-removal surgery. The goal is to see if the drug can dampen …

This study tests whether a consumer smartwatch (Apple Watch or Samsung Galaxy Watch) can continuously monitor people with leptomeningeal metastasis, a condition where cancer spreads to the fluid and membranes around the brain and spinal cord. The watch collects data on movement a…

This study tests a surgical technique called lymphaticovenous bypass (LVB) to prevent lymphedema (arm swelling) in 400 breast cancer patients whose cancer has spread to lymph nodes. During standard lymph node removal, doctors will also reroute lymph vessels to veins, hoping to re…

This trial compares two FDA-cleared robotic bronchoscopy platforms—Monarch and ION—to see which one better diagnoses suspicious spots in the lungs. About 400 people scheduled for a robotic bronchoscopy will be randomly assigned to one of the two systems. The main question is whic…

This study explores whether a personalized music therapy session, called music-assisted relaxation and imagery (MARI), can reduce pain and change gene activity in people recovering from open surgery for stomach, pancreas, bile duct, liver, or peritoneal cancer. Participants will …

This pilot study tests whether a daily transanal irrigation (TAI) routine can help people who have bowel urgency, leakage, and diarrhea after rectal cancer surgery (low anterior resection syndrome). Sixty adults who have had a temporary ileostomy and are about to have it closed w…

This pilot study tests whether freeze-dried miracle fruit (MiraBurst) can improve taste changes in people with solid tumors undergoing cancer treatment. About 45 adults will take one mini-square before each meal for 90 days. The goal is to see if this simple supplement can ease a…

This study tests a daily digital mindfulness program designed to reduce depressive symptoms in people who have completed treatment for breast, prostate, or colorectal cancer. Researchers will enroll 76 participants with mild to moderate depression to see if the program is feasibl…

This study planned to test whether kidneys with small, low-risk tumors could be removed from donors, have the tumor taken out, and then be transplanted into patients with kidney failure. The goal was to increase the number of available donor kidneys. However, the study was withdr…

This study will test whether ChatGPT, an artificial intelligence chatbot, can help men better understand their prostate cancer diagnosis. Fifty men who recently had a prostate biopsy will use the chatbot to review their pathology results. Researchers will measure how accurately p…

This study surveys 240 breast cancer patients to understand how they use herbs and supplements alongside standard treatments like chemo or hormone therapy. Researchers want to see if ethnicity influences which products people take. The goal is to gather information, not to test a…