Experimental drug aims to destroy Amyloid-Causing cells in newly diagnosed patients

NCT ID NCT07524634

First seen Apr 23, 2026 · Last updated May 16, 2026 · Updated 2 times

Summary

This study tests an experimental drug called elranatamab in people newly diagnosed with light chain (AL) amyloidosis who have not yet had treatment. The drug works by helping the body's immune cells find and destroy the abnormal plasma cells that cause the disease. Researchers want to see if it can produce deep remissions and improve organ function, and they will compare two different dosing schedules. About 64 participants will receive the drug as injections under the skin over 6 months, with follow-up for up to 2 years.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AMYLOID LIGHT-CHAIN AMYLOIDOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic

    Rochester, Minnesota, 55902, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.