Music may soothe pain at the genetic level after cancer surgery
NCT ID NCT07653594
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether a personalized music therapy session, called music-assisted relaxation and imagery (MARI), can reduce pain and change gene activity in people recovering from open surgery for stomach, pancreas, bile duct, liver, or peritoneal cancer. Participants will receive a 30-minute live guitar session with guided imagery on the day after surgery and at another time they choose. Researchers will collect blood samples before and after the therapy to look for changes in gene expression linked to pain relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Music-assisted relaxation and imagery (MARI)
What this could lead to
If this approach works, it could offer a drug-free way to manage pain after major cancer surgery.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply to everyone. It is designed to test feasibility, not prove effectiveness.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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