Case Comprehensive Cancer Center
Clinical trials sponsored by Case Comprehensive Cancer Center, explained in plain language.
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New approach targets immune system to fight returning brain tumors
Disease control CompletedThis early-stage study tested whether two existing drugs, given at low doses, could help control aggressive brain tumors that have returned after previous treatment. The goal was to see if the drugs could reduce certain immune cells that suppress the body's natural defenses again…
Phase: PHASE1 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Sleep apnea device repurposed to shield organs during cancer radiation
Disease control CompletedThis study tested whether a common breathing device (CPAP) could make radiation therapy safer for people with lung cancer or left-sided breast cancer. Researchers wanted to see if using the CPAP device during treatment planning could reduce the amount of radiation that reaches he…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Drug trial aims to shrink tumors before surgery, hoping to avoid recurrence
Disease control CompletedThis small, early-stage study tested if giving the immunotherapy drug pembrolizumab before surgery could help treat a serious form of skin cancer called basal cell carcinoma on the head and neck. The goal was to see if the drug could shrink the tumors, make surgery more effective…
Phase: PHASE1 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Researchers test quicker, gentler treatment for Sun-Damaged skin
Disease control CompletedThis study tested whether a common light therapy for sun-damaged skin (actinic keratosis) could be made less painful by shortening the treatment time. Researchers compared three different treatment durations (10, 20, and 60 minutes) to see if the shorter times could still effecti…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Phone-Based coaching helps cancer survivors shed weight and boost health
Disease control CompletedThis study tested a personalized counseling program to help breast cancer survivors manage their weight and improve their health. The program combined in-person and phone-based coaching on diet and exercise. Researchers wanted to see if this more convenient approach could help pa…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Modified drug cocktail tested to boost leukemia transplant success
Disease control CompletedThis study tested a modified three-drug combination given to patients before a stem cell transplant from a partially matched or cord blood donor. The goal was to see if this adjusted regimen could improve survival and reduce severe side effects for people with high-risk blood can…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Silent threat: new swallow test aims to catch dangerous esophagus condition before It's too late
Diagnosis CompletedThis study tested a new office-based swallow test called EsoCheck/EsoGuard to detect Barrett's esophagus in people at risk who don't have chronic heartburn symptoms. Researchers enrolled about 500 adults over age 50 with specific risk factors but no regular heartburn. The goal wa…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Diagnosis
Last updated Mar 30, 2026 14:27 UTC
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New program tackles barriers to Life-Saving colon cancer checks in High-Risk community
Prevention CompletedThis study tested an 11-step community program designed to help more African Americans get screened for colon cancer. It worked with 163 people aged 45-75 who were overdue for screening, providing education, risk assessment, and practical help to overcome common barriers like cos…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Prevention
Last updated Mar 17, 2026 13:09 UTC
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Calming scent tested to ease surgery fears
Symptom relief CompletedThis study tested whether the smell of lavender could help patients feel less anxious during a common skin cancer surgery. Researchers enrolled 89 adults having surgery on their face or neck to see if the calming scent reduced their nervousness and their perception of bad smells …
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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New program aims to ease the burden on cancer caregivers
Symptom relief CompletedThis study tested whether a special education and support program could help family caregivers feel more confident and less stressed while caring for a loved one with cancer. Researchers compared the new program to usual care for about 180 patient-caregiver pairs. The goal was to…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Healing hands? study tests reiki for cancer pain relief
Symptom relief CompletedThis small study tested whether Reiki, a hands-on relaxation therapy, could help improve common symptoms like pain and fatigue for cancer patients. It involved 10 patients at a supportive care clinic who received six Reiki sessions. The main goal was to see if the therapy was pra…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Camera watches skin treatment to predict success
Knowledge-focused CompletedThis study tested a special video camera during a standard light therapy treatment for sun-damaged skin patches called actinic keratoses. Researchers wanted to see if the camera could measure certain signals in the skin to predict how well the treatment would work. The goal was t…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Scientists seek blood clues to stop cancer treatment bleeding
Knowledge-focused CompletedThis study collected a single blood sample from 40 adult cancer patients with very low platelet counts. The goal was to provide fresh blood for lab testing of a potential future artificial platelet product. This research aims to help develop treatments that could reduce bleeding …
Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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AI steps in: testing new counseling for breast cancer genetics
Knowledge-focused CompletedThis study aimed to understand if an artificial intelligence (AI) program could be as effective as traditional in-person counseling for genetic testing discussions. It involved 35 women recently diagnosed with breast cancer who did not typically qualify for such testing under sta…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Breaking barriers: navigators help black patients finish cancer treatment
Knowledge-focused CompletedThis study tested whether patient navigators could help Black breast and prostate cancer patients complete their radiation therapy. Researchers worked with 30 Black patients to understand what barriers prevent treatment completion and whether navigator support makes a difference.…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC