Case Comprehensive Cancer Center
Clinical trials sponsored by Case Comprehensive Cancer Center, explained in plain language.
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New hope for recurrent brain cancer: drug combo targets immune suppressors
Disease control CompletedThis early-phase study tested a combination of two drugs (low-dose capecitabine and bevacizumab) in 12 people whose glioblastoma brain tumors had returned or worsened despite prior treatment. The goal was to see if the treatment could reduce certain immune cells (MDSCs) that help…
Phase: PHASE1 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 03:15 UTC
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Personalized diet and exercise program shows promise for breast cancer survivors
Disease control CompletedThis study tested a personalized nutrition and physical activity counseling program for breast cancer survivors who were overweight. The program included both in-person and phone sessions to make it easier to participate. The goal was to help participants lose weight, improve bod…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 03:09 UTC
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Immunotherapy before surgery shows promise for tough skin cancers
Disease control CompletedThis study tested whether giving the immunotherapy drug pembrolizumab before surgery could help shrink advanced basal cell carcinoma on the head and neck. 13 adults with high-risk skin cancer received the drug, then had surgery to remove any remaining tumor. The goal was to see i…
Phase: PHASE1 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New chemo cocktail shows promise in leukemia transplant trial
Disease control CompletedThis study tested adding a drug called thiotepa to the usual chemo given before a donor stem cell transplant for people with leukemia. The goal was to see if this stronger mix could help more patients stay cancer-free one year later. The trial involved 40 patients and focused on …
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 19:36 UTC
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No heartburn? no problem: new test spots hidden esophagus risk
Diagnosis CompletedThis study tested a new, quick office-based test to find Barrett's esophagus in people who don't have typical heartburn symptoms. Researchers looked at 132 adults over 50 with other risk factors like being male, white, or having a large waist. The goal was to see if the test coul…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Diagnosis
Last updated May 14, 2026 12:03 UTC
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New training boosts cancer caregiver confidence
Symptom relief CompletedThis study tested whether an education and support program can help family caregivers of people with cancer feel more confident in their caregiving skills and less anxious. About 484 caregivers and patients took part. Researchers compared different types of support to see which w…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 03:13 UTC
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Reiki shows promise for easing cancer pain and fatigue
Symptom relief CompletedThis study looked at whether Reiki, a gentle hands-on energy therapy, could help cancer patients manage symptoms like pain and fatigue. Ten adults with cancer who had at least three moderate-to-severe symptoms received six Reiki sessions. The main goal was to see if the approach …
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 03:10 UTC
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Quick fix for Sun-Damaged skin: shorter light therapy may cut pain without losing punch
Symptom relief CompletedThis study tested whether shorter incubation times for a topical gel (10% ALA) before red-light therapy could reduce pain while still clearing actinic keratoses—rough, scaly spots caused by sun damage. Thirty adults with at least 10 facial lesions were randomly assigned to have t…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 03:01 UTC
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Lavender power: simple scent eases anxiety during skin cancer surgery
Symptom relief CompletedThis study tested whether smelling lavender during Mohs surgery for skin cancer helps lower anxiety and reduce the perception of unpleasant odors. 89 adults having surgery on their head or neck took part. Researchers measured anxiety using standard questionnaires and a visual sca…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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Virtual reality goggles offer escape from chemo anxiety
Symptom relief CompletedThis study tested whether using a virtual reality headset during a single chemotherapy session could help cancer patients feel less distressed, anxious, or in pain. 68 adults with any type of cancer and high distress levels were randomly assigned to either use virtual reality for…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 08, 2026 12:02 UTC
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Blood draw study aims to unlock secrets of low platelets
Knowledge-focused CompletedThis study collected one blood sample from 40 adults with very low platelets (30,000/mcl or less) due to blood cancers or their treatment. The goal was to gather samples for research, not to provide treatment. Participants could not have had chemotherapy in the last 24 hours or b…
Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:16 UTC
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AI takes on genetic counseling for breast cancer patients
Knowledge-focused CompletedThis study looked at whether an artificial intelligence program could effectively provide genetic counseling to women newly diagnosed with breast cancer who do not meet current guidelines for genetic testing. Researchers compared the AI approach to traditional in-person counselin…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:09 UTC
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New program aims to boost mammogram rates among homeless women
Knowledge-focused CompletedThis study tested a community-based program to help homeless women get mammograms and overcome barriers to breast cancer screening. Researchers worked with 203 women living in shelters or transitional housing to see if education and support could increase screening rates. The goa…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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New program aims to close the gap in colorectal cancer screening for african americans
Knowledge-focused CompletedThis study tested a community-based program to help African Americans aged 45-75 get screened for colorectal cancer. The program provided education, risk assessment, and help with barriers like finding a doctor, transportation, and appointment scheduling. Researchers measured whe…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Study tests navigator program to close radiation gap for black cancer patients
Knowledge-focused CompletedThis pilot study looked at whether a patient navigator could help Black breast and prostate cancer patients complete a shorter course of radiation therapy. The study enrolled 30 African-American adults with these cancers. Researchers used surveys to understand barriers to care an…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Could a sleep apnea device shield lungs during cancer radiation?
Knowledge-focused CompletedThis small study looked at whether using a CPAP machine during radiation therapy can reduce the amount of radiation reaching the lungs in people with left-sided breast cancer or lung cancer. Eight patients were enrolled to compare lung radiation doses with and without CPAP. The g…
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC
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Can a camera predict skin treatment success?
Knowledge-focused CompletedThis study tested a new video device that takes pictures of actinic keratoses (rough, scaly skin patches) during light therapy. The goal was to see if the device could predict how well the treatment works by measuring certain chemicals in the skin. Fourteen adults with at least 1…
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC