Case Comprehensive Cancer Center

This early-phase study tested whether adding the experimental drug ruxolitinib to standard radiation and chemotherapy (temozolomide) is safe for people with newly diagnosed high-grade gliomas or glioblastoma. Ruxolitinib targets proteins that help cancer cells grow. The study enr…

This study tested a pill called abemaciclib in 14 people with certain lung cancers (like small cell lung cancer) that stopped responding to chemotherapy. The goal was to see if the drug could shrink tumors and to check its safety. While the drug targets a specific protein to slow…

This early-phase study tested a combination of two drugs (low-dose capecitabine and bevacizumab) in 12 people whose glioblastoma brain tumor had come back or continued growing despite prior treatment. The goal was to see if the drugs could reduce certain immune cells (MDSCs) that…

This study tested adding a drug called thiotepa to the usual chemotherapy given before a donor stem cell transplant for people with leukemia. The goal was to see if this stronger mix could help more patients stay cancer-free one year after the transplant. The study included 40 ad…

This early-phase trial tested the immunotherapy drug pembrolizumab in 13 people with advanced basal cell carcinoma of the head and neck. Participants received the drug before and after surgery to see if it could shrink tumors and improve outcomes. The goal was to understand how t…

This study tested a 6-month personalized nutrition and exercise counseling program for breast cancer survivors who are overweight. The program included meetings with a dietitian and a tailored physical activity plan. Researchers wanted to see if participants could lose 10% of the…

This study tested a new, office-based test called EsoCheck/EsoGuard to detect Barrett's esophagus in 132 people who do not have chronic heartburn but have other risk factors like being over 50, white, male, or having central obesity. Participants swallowed a capsule on a string t…

This study tested whether using a virtual reality headset during chemotherapy can reduce distress, anxiety, and pain. 68 cancer patients were randomly assigned to either use VR for 15–30 minutes or receive standard care. Researchers measured changes in distress and pain scores be…

This study tested whether an education and support program can help family caregivers of cancer patients feel more confident and less anxious. About 484 caregivers and patients took part. Researchers compared different types of support to see which worked best.

This study tested whether smelling lavender essential oil during Mohs surgery for skin cancer can reduce patient anxiety and mask unpleasant odors. 89 adults having surgery on their head or neck took part. Researchers measured anxiety using standard questionnaires and asked about…

This study tested whether Reiki, a relaxation therapy where a practitioner places hands on or near the body, could help cancer patients with symptoms like pain and fatigue. Ten adults with cancer who had at least three bothersome symptoms received up to six Reiki sessions. Resear…

This study tested whether shorter incubation times for a topical gel (10% ALA) before red-light photodynamic therapy (PDT) could reduce pain while still effectively clearing actinic keratoses (AKs) on the face. Thirty adults with at least 10 AK lesions were randomly assigned to h…

This study tested a community-based program to help homeless women complete mammograms for breast cancer screening. Researchers surveyed 203 women living in shelters and provided a brief educational session on breast health. The goal was to identify and overcome barriers to scree…

This study looked at 35 women with early-stage breast cancer who do not currently qualify for genetic testing under standard guidelines. It compared the use of an artificial intelligence program for pre-test genetic counseling versus traditional in-person counseling. The goal was…

This study tested an 11-step community program to help African Americans get screened for colorectal cancer. The program included education, risk assessment, and help with barriers like cost, transportation, and scheduling. 163 participants joined, and the study measured whether …

This study tested a new video device that takes images of skin lesions during photodynamic therapy (PDT) for actinic keratoses, a common precancerous skin condition. The goal was to see if the device could predict how well the treatment works by measuring certain chemicals in the…

This study looked at whether using a CPAP machine (commonly used for sleep apnea) during radiation therapy can reduce the amount of radiation reaching the lungs. Eight people with left-sided breast cancer or lung cancer took part. Researchers compared lung radiation doses with an…

This pilot study tested a patient navigator program for African-American adults with breast or prostate cancer. The goal was to see if having a navigator helps patients understand their treatment options and complete radiation therapy as planned. The study enrolled 30 people and …

This study collected one blood sample from 40 adults with very low platelets (30,000 or fewer per microliter) due to blood cancers or their treatments. The goal was simply to gather samples for research, not to test any new drug or therapy. Participants had to be 18 or older and …