New camera could predict skin treatment success

NCT ID NCT05923060

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new video device that takes images of skin lesions during photodynamic therapy (PDT) for actinic keratoses, a common precancerous skin condition. The goal was to see if the device could predict how well the treatment works by measuring certain chemicals in the skin. Fourteen adults with at least 10 lesions on their arms or legs took part. The device was used alongside standard PDT to monitor the treatment in real time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aminolevulinic acid (topical)

What this could lead to

If successful, this imaging technique could help doctors predict which skin lesions will respond best to photodynamic therapy, making treatment more personalized and effective.

What could go wrong

This was a very small, early-phase study with only 14 participants. The device's ability to predict treatment success is still unproven, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

actinic keratosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44195, United States