Shorter PDT may cut pain without losing punch against precancerous spots
NCT ID NCT06027619
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether shorter incubation times for a topical gel (10% ALA) before red-light photodynamic therapy (PDT) could reduce pain while still effectively clearing actinic keratoses (AKs) on the face. Thirty adults with at least 10 AK lesions were randomly assigned to have the gel left on for 10, 20, or 60 minutes before light exposure. The goal was to find a less painful treatment that remains effective.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic, Dermatology and Plastic Surgery Institute, Case Comprehensive Cancer Center
Cleveland, Ohio, 44195, United States
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