New Light-Activated gel aims to clear precancerous skin spots
NCT ID NCT07144345
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a reformulated gel (Levulan Kerastick) combined with blue light therapy to treat actinic keratosis, a common precancerous skin condition. About 160 adults with 4 to 8 mild-to-moderate spots on the face or bald scalp will receive either the active gel or a placebo gel, followed by blue light. The main goal is to see how many people have all their spots cleared after 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
aminolevulinic acid hydrochloride (ALA HCl) 20% solution applied to the skin, then activated by blue light
What this could lead to
If successful, this could offer a more effective field treatment for actinic keratosis, reducing precancerous spots on the face or scalp.
What could go wrong
This is a Phase 3 trial, but results may not confirm superiority over existing treatments. Skin reactions and incomplete clearance are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Arlington Dermatology
RECRUITINGRolling Meadows, Illinois, 60008, United States
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Center for Clinical and Cosmetic Research
RECRUITINGAventura, Florida, 33180, United States
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Center for Dermatology Clinical Research, Inc
RECRUITINGFremont, California, 94538, United States
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Medisearch, LLC
RECRUITINGSaint Joseph, Missouri, 64506, United States
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Minnesota Clinical Study Center
RECRUITINGNew Brighton, Minnesota, 55112, United States
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Oregon Dermatology and Research Center
RECRUITINGPortland, Oregon, 97210, United States
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Palmetto Clinical Trial Services, LLC
RECRUITINGGreenville, South Carolina, 29615, United States
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Premier Clinical Research
RECRUITINGSpokane, Washington, 99202, United States
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Tennessee Clinical Research Center
RECRUITINGNashville, Tennessee, 37215, United States
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The Indiana Clinical Trials Center, PC
RECRUITINGPlainfield, Indiana, 46168, United States