Laser and immunotherapy combo takes on deadly brain tumors

NCT ID NCT03277638

First seen Jan 11, 2026 · Last updated May 02, 2026 · Updated 16 times

Summary

This study tests a new approach for adults with recurrent glioblastoma, an aggressive brain cancer. It combines a minimally invasive laser that heats and destroys tumor tissue (LITT) with pembrolizumab, an immunotherapy drug that helps the immune system fight cancer. The goal is to see if this combination is safe and improves tumor shrinkage and survival compared to standard treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.