Biontech Se

This early-stage study tested a new RNA-based vaccine designed to protect against mpox (monkeypox). Researchers enrolled 96 healthy adults, including some who had received a smallpox vaccine decades ago and some who had not. The main goal was to check the vaccine's safety and see…

This study tested the safety and immune response of the Pfizer-BioNTech COVID-19 vaccine in 960 healthy Chinese adults. Participants received either two doses of the vaccine or a placebo shot, with researchers tracking their antibody levels and any side effects for about a year. …

This early-stage trial tested the safety of two new tuberculosis vaccine candidates in healthy adults who had never received the standard BCG vaccine. Researchers gave 120 participants different dose levels of the experimental vaccines or a placebo to check for side effects and i…

This large study tested several versions of an mRNA vaccine to prevent COVID-19. It involved nearly 47,000 healthy volunteers, including teenagers and older adults. The main goal was to find the safest and most effective dose and schedule, leading to the authorization of the wide…

This study tested updated versions of the Pfizer/BioNTech COVID-19 vaccine designed to protect against newer virus variants like Omicron. It involved over 1,400 healthy adults and teens who had already been vaccinated. The main goals were to check the safety of these new booster …

This study tested new mRNA vaccine candidates designed to protect against influenza and COVID-19. Researchers gave healthy adults a single shot containing either a flu vaccine, a COVID vaccine, or a mix of both. The main goals were to check the safety of the vaccines and see how …

This early-stage trial tested a new investigational RNA-based COVID-19 vaccine, called BNT162b4, in 383 healthy adults who had already received previous COVID-19 shots. The main goal was to check the safety and side effects of different doses, given alone or combined with existin…

This was a first-in-human study to test the safety and immune response of a new RNA-based malaria vaccine called BNT165b1. The trial enrolled 60 healthy adults to receive one of three dose levels or a placebo. The main goal was to find a safe and tolerable dose for future develop…

This large, completed Phase 3 trial tested a new single vaccine designed to protect against both COVID-19 and seasonal influenza. Nearly 9,000 healthy adults received either the combined shot or separate standard vaccines to compare safety and immune response. The goal is to see …

This study tested a new combination treatment for people with advanced melanoma that had stopped responding to standard immunotherapy. It combined an experimental cancer vaccine (BNT111) with an existing immunotherapy drug (cemiplimab) to see if it could shrink tumors. The trial …

This early-stage trial tested two personalized RNA vaccines designed to train the immune system to fight triple-negative breast cancer. The study involved 42 patients who received vaccines tailored to their specific tumor characteristics. Researchers aimed to determine if these c…

This was the first-ever study in people to test the safety and early effects of two new cancer drugs, BNT152 and BNT153, developed by BioNTech. It involved 86 adults with advanced solid tumors that had spread or could not be removed by surgery, and for whom standard treatments we…

This large, completed study aimed to see if giving extra doses of the Pfizer-BioNTech COVID-19 vaccine to people who were already vaccinated was safe and effective. It involved over 16,000 healthy participants across multiple countries and tested different booster doses, includin…