New TB vaccines enter human testing – could they prevent a global killer?

NCT ID NCT05537038

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested two experimental vaccines (BNT164a1 and BNT164b1) against tuberculosis in 120 healthy adults who had never been exposed to TB or received the BCG vaccine. The main goal was to check safety and find the best dose. Participants received three doses of either a vaccine or a placebo, and researchers monitored side effects and immune responses for several months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CRS Clinical Research Services Berlin GmbH

    Berlin, 13627, Germany

  • CRS Clinical Research Services Mannheim GmbH

    Mannheim, 68167, Germany

  • emovis GmbH

    Berlin, 10629, Germany