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This study is testing two new investigational vaccines designed to protect against tuberculosis (TB). Researchers are evaluating the safety and immune response of different dose levels in healthy adults who have previously received the standard BCG vaccine. The goal is to find a …

This study is testing an updated COVID-19 vaccine designed for the 2025-2026 season in children aged 5 to 11 who have a medical condition that puts them at high risk for severe COVID-19. Researchers want to see how safe the vaccine is and how well it triggers an immune response. …

This study is testing an updated COVID-19 vaccine designed for the 2025-2026 virus season. It aims to check the safety and how well it triggers an immune response. The trial is enrolling 760 people aged 12 and older who are at higher risk for severe COVID-19, including all adults…

This study is testing a new drug called BNT327, given alongside standard chemotherapy, for people with a fast-growing type of lung cancer called small-cell lung cancer. It is for two groups: people who have not yet received treatment for their advanced cancer, and people whose ca…

This is the first study in people to test the safety of a new cancer drug called BNT314. It involves 41 adults with advanced solid tumors that have progressed after standard treatments. The main goal is to find the highest dose that is safe and manageable, while also looking for …

This study is testing a new drug called BNT327, given alongside standard chemotherapy, for people with advanced triple-negative breast cancer. The main goals are to see if the combination is safe and if it helps shrink tumors. The trial will enroll about 83 adults who have either…

This is an early-stage study to test the safety and immune response of a new vaccine designed to prevent painful genital herpes outbreaks. The trial will enroll healthy adults and people with a history of recurrent genital herpes to receive the vaccine or a placebo. Researchers w…