VENOUS THROMBOEMBOLISM

This study compared two blood thinners, rivaroxaban (Xarelto) and apixaban (Eliquis), in 2760 adults with new blood clots in the legs or lungs. The goal was to see which drug causes fewer bleeding problems. Results could help doctors choose the safer option for treating venous th…

This pilot study tested whether a shorter course of blood thinner (LMWH) followed by aspirin is as good as the standard 6 weeks of LMWH for preventing blood clots after childbirth. The study enrolled 30 women at moderate to high risk of clots. The main goal was to see if women wo…

This large, completed phase 3 trial enrolled over 5,400 people undergoing total hip or knee replacement to compare two approaches for preventing venous thromboembolism (blood clots). Participants received either aspirin alone or a short course of rivaroxaban followed by aspirin. …

This study tested a special sheath (the Protrieve Sheath) placed in a large vein to catch any blood clots that might break loose during a procedure to remove deep vein clots (DVT). The goal was to prevent those clots from reaching the lungs and causing a pulmonary embolism. The s…

This study looked at whether the blood thinner Xarelto (rivaroxaban) can prevent dangerous blood clots in the legs or lungs after hip or knee replacement surgery. 150 patients were randomly assigned to receive either Xarelto or no blood thinner after surgery. The researchers trac…

This study tested a special filter placed in a large vein to catch blood clots before they reach the lungs. It included 50 people who could not take blood thinners. The goal was to see how often the filter could be successfully placed and removed, and to track any problems.

This study compared two common blood thinners, rivaroxaban and apixaban, in 72 adults with newly diagnosed blood clots in the legs or lungs. The main goal was to see if a larger trial is possible by checking how many patients could join and complete follow-ups. Researchers also t…

This study looked at whether a low dose of the blood thinner apixaban (2.5 mg twice daily for 12 months) can safely prevent blood clots from returning in people who already had a clot triggered by a temporary risk factor. 600 high-risk adults took either apixaban or a placebo. Th…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study tested a new rapid D-dimer blood test (LumiraDx) in 679 people with symptoms of deep vein thrombosis or pulmonary embolism. The test uses a small blood sample from a finger prick or vein to quickly measure D-dimer levels, which can help rule out dangerous blood clots. …

This study tested an experimental drug called REGN7508 in 179 adults having knee replacement surgery. The goal was to see if it could prevent blood clots in the legs or lungs better than standard care. Researchers also monitored side effects and how the drug moved through the bod…

This study tested two experimental drugs, REGN9933 and REGN7508, to see if they can prevent venous thromboembolism (blood clots) in adults who need a PICC line for at least 14 days. The drugs are monoclonal antibodies that target a clotting factor. 195 participants received a sin…

This study tested whether a small, wearable device called geko can help prevent dangerous blood clots in the legs of critically ill adults. The geko device uses mild electrical pulses to stimulate leg muscles, improving blood flow. Researchers compared it to standard compression …

This study tested whether a special nursing plan (called ERAS) could help women recover after surgery for cervical cancer. 160 women were split into two groups: one got the ERAS nursing plan, the other got standard care. The goal was to see if the ERAS plan could lower the risk o…

This study examined blood samples from 119 adults with sickle cell disease, sickle cell trait, or no condition to understand why some develop dangerous blood clots. Participants gave blood and had health check-ins over two years. The goal was to find biomarkers that could lead to…

This study measured how two common blood thinners (rivaroxaban and apixaban) behave in 193 adults with active cancer who also had blood clots or atrial fibrillation. Researchers aimed to understand factors like age, weight, and kidney function that affect drug levels. The goal wa…

This study used data from over 12,000 ICU patients to create a computer model that can predict which patients are at risk for venous thromboembolism (VTE) – dangerous blood clots. The model was designed to be easy for doctors to understand and use. The goal is to improve preventi…

This study looks at data from children under 18 in Japan who were prescribed either rivaroxaban or warfarin for blood clots. Researchers want to see how often major bleeding happens in real-world use. No new treatments are given—only existing medical records are reviewed.

This study looked at whether sending alerts to pharmacists instead of doctors helps improve how blood thinners (anticoagulants) are prescribed. Researchers tested two types of alerts with 306 healthcare providers. The goal was to see which method leads to faster and safer prescri…

This completed study followed 1,000 adults with venous thromboembolism (blood clots) across China for several years. Researchers tracked who had another clot, who had bleeding problems, and who died. The goal was to learn which patients need long-term blood-thinning medication an…

This study interviewed 15 children aged 12 to 21 who have bleeding or clotting disorders. Researchers asked about their quality of life, confidence in managing their condition, and how they view the care they receive. The goal is to better understand the real-life challenges thes…

This completed study examined stored DNA from 150 adults over 50 who had a history of venous thromboembolism (blood clots). Researchers looked for specific gene mutations linked to a condition called clonal hematopoiesis of indeterminate potential (CHIP). The goal was to see how …

This completed study looked at whether intimate partner violence (IPV) increases the risk of blood clots in women taking combined oral contraceptives. Researchers compared 997 women who had a first blood clot with similar women who did not, using a questionnaire to screen for IPV…

This study looked at whether levels of nucleosomes and free DNA in the blood change from month to month in healthy people and in those who have had a blood clot (venous thromboembolism). Researchers measured these markers monthly for six months in 15 healthy volunteers and 15 pat…

This study tracked 81 adults with pelvic or hip socket fractures to see how often they developed blood clots in their legs or lungs, even while receiving standard clot-preventing medication. All participants got ultrasound scans to find clots that might not cause symptoms. The go…

This study looked at 744 people who had a blood clot before and were suspected of having another one. Researchers tested three different checklists (called clinical decision rules) to see how well they could tell if a new clot was really there. The goal was to help doctors avoid …