VENOUS THROMBOEMBOLISM

This study tested whether taking a low dose of the blood thinner apixaban for a longer time could prevent blood clots from returning in people who already had a clot caused by a temporary risk factor (like surgery or immobility). 600 adults at high risk for another clot were rand…

This study compared two blood thinners, rivaroxaban and apixaban, to see which causes less bleeding in people with blood clots. About 2,760 adults with new clots in their legs or lungs took part. The goal was to find out which drug is safer, since both are already approved but ha…

This study looked at whether the blood thinner Xarelto (rivaroxaban) can safely prevent dangerous blood clots in the legs or lungs after total hip or knee replacement surgery. 150 patients in Taiwan were randomly assigned to receive Xarelto or standard care. The researchers measu…

This study tested two experimental drugs (REGN9933 and REGN7508) to see if they can prevent blood clots in adults who need a PICC line (a thin tube placed in a vein). The study involved 195 participants and compared the drugs to a placebo. Researchers monitored for clots, side ef…

This study tested a special sheath (Protrieve) placed in a large vein to catch any blood clots that might break loose during a procedure to remove deep vein clots (DVT). The goal was to prevent those clots from traveling to the lungs and causing a pulmonary embolism. The study in…

This study tested an experimental drug called REGN7508 in 179 adults having knee replacement surgery. The goal was to see if it could prevent blood clots in the legs or lungs. Researchers compared the drug to standard care and monitored for side effects and how the drug behaved i…

This study tested whether a small device called Geko, which uses mild electrical pulses to make leg muscles twitch, can prevent dangerous blood clots in critically ill adults. It compared the Geko device to standard compression boots (IPCs) in 40 ICU patients. The goal was to see…

This study talked to children aged 12 to 21 with bleeding or clotting disorders to understand how their condition affects their daily life, emotions, and future plans. Researchers used interviews and questionnaires to learn about quality of life, confidence in managing their diso…

This study checked 150 adults over 50 with a history of venous thromboembolism (blood clots) for certain genetic mutations in their blood cells. The goal was to see if these mutations, known as clonal hematopoiesis of indeterminate potential (CHIP), are common in this group. Rese…

This study tested whether sending safety alerts to pharmacists instead of doctors leads to faster changes in blood thinner prescriptions. Researchers enrolled 306 healthcare providers and compared how quickly each group responded to alerts. The goal was to find the best way for d…

This study tracked 81 adults with pelvic or hip socket fractures to see how many developed dangerous blood clots despite receiving standard clot-preventing medication. All participants got twice-daily enoxaparin shots and were screened with ultrasound. The goal was to measure clo…

This study looks at medical records of children under 18 in Japan who were prescribed rivaroxaban or warfarin for blood clots. Researchers want to see how often serious bleeding happens with each drug in everyday care. No extra tests or visits are needed—only existing health data…

This study followed 1,000 people who had a blood clot in their veins (venous thromboembolism) for several years. Researchers wanted to find out which patients need long-term blood-thinning medication and understand the long-term outlook. Participants had yearly check-ups by phone…

This study looked at whether two blood markers (nucleosomes and free DNA) stay stable over time in healthy people and in people who have had a blood clot. Researchers measured these markers monthly for six months in 15 healthy volunteers and 15 patients with a history of venous t…

This study looked at 744 people who had a blood clot before to see if doctors can better predict when a new clot will happen. Researchers tested three different checklists (called clinical decision rules) to see how well they work. The goal is to help doctors correctly diagnose n…

This study compared two common blood thinners, rivaroxaban and apixaban, to see which causes less bleeding in people with blood clots. It involved 72 adults with new clots in the legs or lungs. The main goal was to test if a larger study is possible, not to declare a winner.