New device aims to catch clots during DVT procedure, prevent lung damage

NCT ID NCT06495996

Completed Disease control Sponsor: Inari Medical Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study tested a special sheath (the Protrieve Sheath) placed in a large vein to catch any blood clots that might break loose during a procedure to remove deep vein clots (DVT). The goal was to prevent those clots from reaching the lungs and causing a pulmonary embolism. The study included 66 people at high risk for such complications. Researchers measured how well the device captured clots and whether it caused any serious side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Protrieve Sheath (a device that catches blood clots during a procedure to remove deep vein clots)
What this could lead to: If it works, this device could reduce the risk of a blood clot traveling to the lungs during DVT treatment, making the procedure safer.
What could go wrong: This was a small, single-arm study with no comparison group, so results may not be definitive. The device itself carries risks like bleeding or damage to blood vessels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism Venous Thrombosis pulmonary embolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP VENOUS THROMBOSIS VENOUS THROMBOEMBOLISM

Contacts and locations

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Locations

Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
Baptist Health South Florida

Miami, Florida, 33176, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Englewood Hospital

Englewood, New Jersey, 07631, United States
Hoag Hospital

Newport Beach, California, 92663, United States
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
IU Health Methodist Hospital

Indianapolis, Indiana, 46204, United States
MedStar Union Memorial Hospital

Baltimore, Maryland, 21218, United States
NYU Langone Medical Center

New York, New York, 10016, United States
University Medical Center Southern Nevada

Las Vegas, Nevada, 89102, United States
University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States
University of Texas Medical Branch

Galveston, Texas, 77555, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37203, United States
West Virginia University Hospital

Morgantown, West Virginia, 26506, United States
Yale University

New Haven, Connecticut, 06510, United States

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