Massive study tests if insurance records can mimic Gold-Standard drug trials
NCT ID NCT04736420
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at healthcare claims from over 78,000 people to see if it can reproduce the results of the EINSTEIN-DVT trial, which compared two blood thinners (rivaroxaban and warfarin) for treating blood clots. The goal is not to test a new drug, but to learn whether real-world data can reliably mimic clinical trials. If it works, this approach could help researchers answer questions faster and cheaper using existing health records.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rivaroxaban and Warfarin
What this could lead to
If successful, this could show that analyzing healthcare claims data can reliably reproduce clinical trial results, potentially speeding up future research.
What could go wrong
This is an observational study using existing data, not a new treatment trial. Results may not perfectly match the original trial due to data limitations or unmeasured factors.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02120, United States