Massive study tests if insurance records can mimic Gold-Standard drug trials
NCT ID NCT04736420
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study looks at healthcare claims from over 78,000 people to see if it can reproduce the results of the EINSTEIN-DVT trial, which compared two blood thinners (rivaroxaban and warfarin) for treating blood clots. The goal is not to test a new drug, but to learn whether real-world data can reliably mimic clinical trials. If it works, this approach could help researchers answer questions faster and cheaper using existing health records.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rivaroxaban and Warfarin
- What this could lead to
- If successful, this could show that analyzing healthcare claims data can reliably reproduce clinical trial results, potentially speeding up future research.
- What could go wrong
- This is an observational study using existing data, not a new treatment trial. Results may not perfectly match the original trial due to data limitations or unmeasured factors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02120, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Simple 5-Step nursing plan could slash deadly clot risk after hip surgery
- Timing of blood thinners after childbirth bleeding may prevent clots without causing more harm
- Shorter blood thinner course after birth may be just as safe
- New scan may predict dangerous clot return in lung patients