New shot may stop dangerous clots after knee surgery

NCT ID NCT06454630

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study tested an experimental drug called REGN7508 in 179 adults having knee replacement surgery. The goal was to see if it could prevent blood clots in the legs or lungs. Researchers compared the drug to standard care and monitored for side effects and how the drug behaved in the body.

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Contacts and locations

Locations

  • Budai Irgalmasrendi Korhaz

    Budapest, 1027, Hungary

  • Clinic of Orthopaedics and Paediatric Orthopaedics

    Lodz, Łódź Voivodeship, 92-213, Poland

  • Hospital of Traumatology and Orthopaedics

    Riga, LV-1005, Latvia

  • Klaipeda University Hospital

    Klaipėda, LT-92288, Lithuania

  • Liepaja Regional Hospital

    Liepāja, LV-3414, Latvia

  • Lietuvos sveikatos mokslu universiteto ligonine Kauno klinik

    Kaunas, Kaunas County, LT-50161, Lithuania

  • Lithuanian University of Health Sciences Kaunas Hospital

    Kaunas, LT-48142, Lithuania

  • Multi-profile Hospital for Active Treatment Hearth and Brain EAD

    Pleven, 5800, Bulgaria

  • Multiprofile Hospital For Active Treatment Park Hospital Ltd.

    Plovdiv, 4002, Bulgaria

  • Orto Klinika

    Riga, LV-1005, Latvia

  • Riga's 2nd Hospital

    Riga, LV-1004, Latvia

  • Specjalistyczny Szpital im. E. Szczeklika w Tarnowie

    Tarnów, Lesser Poland Voivodeship, 33-100, Poland

  • Szolnoki MAV Hospital

    Szolnok, 5000, Hungary

  • Vidzemes Hospital

    Valmiera, Valmieras Aprinkis, LV-4201, Latvia

Conditions

Explore the condition pages connected to this study.