New shot may prevent dangerous clots after knee surgery

NCT ID NCT06454630

Completed Prevention Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called REGN7508 in 179 adults having knee replacement surgery. The goal was to see if it could prevent blood clots in the legs or lungs better than standard care. Researchers also monitored side effects and how the drug moved through the body.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENOUS THROMBOEMBOLISM

Contacts and locations

Locations

Budai Irgalmasrendi Korhaz

Budapest, 1027, Hungary
Clinic of Orthopaedics and Paediatric Orthopaedics

Lodz, Łódź Voivodeship, 92-213, Poland
Hospital of Traumatology and Orthopaedics

Riga, LV-1005, Latvia
Klaipeda University Hospital

Klaipėda, LT-92288, Lithuania
Liepaja Regional Hospital

Liepāja, LV-3414, Latvia
Lietuvos sveikatos mokslu universiteto ligonine Kauno klinik

Kaunas, Kaunas County, LT-50161, Lithuania
Lithuanian University of Health Sciences Kaunas Hospital

Kaunas, LT-48142, Lithuania
Multi-profile Hospital for Active Treatment Hearth and Brain EAD

Pleven, 5800, Bulgaria
Multiprofile Hospital For Active Treatment Park Hospital Ltd.

Plovdiv, 4002, Bulgaria
Orto Klinika

Riga, LV-1005, Latvia
Riga's 2nd Hospital

Riga, LV-1004, Latvia
Specjalistyczny Szpital im. E. Szczeklika w Tarnowie

Tarnów, Lesser Poland Voivodeship, 33-100, Poland
Szolnoki MAV Hospital

Szolnok, 5000, Hungary
Vidzemes Hospital

Valmiera, Valmieras Aprinkis, LV-4201, Latvia

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