Can a daily pill prevent dangerous clots after joint surgery?

NCT ID NCT05449327

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether the blood thinner Xarelto (rivaroxaban) can prevent dangerous blood clots in the legs or lungs after hip or knee replacement surgery. 150 patients were randomly assigned to receive either Xarelto or no blood thinner after surgery. The researchers tracked how many developed clots or had complications like bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rivaroxaban (Xarelto)

What this could lead to

If successful, this could confirm that Xarelto is a safe and effective option to prevent blood clots after joint replacement surgery in Taiwanese patients.

What could go wrong

This is a small, completed study with only 150 participants, so results may not apply to everyone. There is also a risk of bleeding or other complications from the drug.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ditmanson Medical Foundation Chiayi Christian Hospital

    Chiayi City, Taiwan, 60002, Taiwan