Can a daily pill prevent dangerous clots after joint surgery?

NCT ID NCT05449327

Completed Disease control Sponsor: Chiayi Christian Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether the blood thinner Xarelto (rivaroxaban) can prevent dangerous blood clots in the legs or lungs after hip or knee replacement surgery. 150 patients were randomly assigned to receive either Xarelto or no blood thinner after surgery. The researchers tracked how many developed clots or had complications like bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Rivaroxaban (Xarelto)
What this could lead to: If successful, this could confirm that Xarelto is a safe and effective option to prevent blood clots after joint replacement surgery in Taiwanese patients.
What could go wrong: This is a small, completed study with only 150 participants, so results may not apply to everyone. There is also a risk of bleeding or other complications from the drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROPLASTY VENOUS THROMBOEMBOLISM

Contacts and locations

Locations

Ditmanson Medical Foundation Chiayi Christian Hospital

Chiayi City, Taiwan, 60002, Taiwan

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