SYSTEMIC SCLEROSIS
Clinical trials for SYSTEMIC SCLEROSIS explained in plain language.
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New hope for scleroderma: experimental drug anifrolumab in Late-Stage trial
Disease control OngoingThis study tests whether anifrolumab, given as a shot under the skin, can help adults with systemic sclerosis (a disease causing skin thickening and organ damage). About 314 people aged 18 to 70 with early-stage disease will receive either the drug or a placebo. The goal is to se…
Matched conditions: SYSTEMIC SCLEROSIS
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Apr 28, 2026 23:51 UTC
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New drug shows promise for rare Skin-Hardening disease
Disease control OngoingThis phase 3 study tests whether the drug MT-0551 can reduce skin thickening in people with systemic sclerosis, a rare autoimmune disease that causes hardening of the skin and internal organs. About 80 adults with moderate skin involvement will receive either MT-0551 or a placebo…
Matched conditions: SYSTEMIC SCLEROSIS
Phase: PHASE3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Apr 28, 2026 23:51 UTC
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Engineered immune cells take on lupus and scleroderma
Disease control OngoingThis study tests a new treatment using donor immune cells (CAR T-cells) that are designed to target and destroy faulty immune cells causing lupus and scleroderma. The goal is to control these severe autoimmune diseases when other treatments have failed. 18 adults with relapsed or…
Matched conditions: SYSTEMIC SCLEROSIS
Phase: NA • Sponsor: The Affiliated Hospital of Xuzhou Medical University • Aim: Disease control
Last updated Apr 28, 2026 23:50 UTC
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AI scans could predict lung trouble in scleroderma patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at 1000 people with systemic sclerosis (scleroderma) to see if a computer can analyze their CT scans and predict if their lung disease will get worse. Researchers will check if certain features on the scans are linked to survival, lung function decline, and devel…
Matched conditions: SYSTEMIC SCLEROSIS
Sponsor: Royal Brompton & Harefield NHS Foundation Trust • Aim: Knowledge-focused
Last updated Apr 28, 2026 23:51 UTC