Engineered immune cells take on autoimmune diseases

NCT ID NCT07155369

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 42 times

Summary

This study tests a new treatment using donor immune cells (CAR T-cells) that are engineered to target and calm the overactive immune system in people with severe lupus or scleroderma. The goal is to see if it is safe and can control the disease. The trial involves 18 adults whose autoimmune disease has not responded to standard treatments.

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Contacts and locations

Locations

  • The Affiliated Hospital of Xuzhou Medical University

    Xuzhou, China

Conditions

Explore the condition pages connected to this study.