Poop pills could ease stomach troubles for scleroderma patients

NCT ID NCT06333795

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether fecal microbiota transplantation (FMT) – giving healthy donor stool in capsules – can safely reduce chronic diarrhea in people with systemic sclerosis. Twenty adults with scleroderma and persistent diarrhea will receive either FMT or a placebo. The main goal is to check for side effects, with a secondary look at whether symptoms improve.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fecal microbiota transplantation (FMT) given as capsules

What this could lead to

If it works, this could offer a new, safe way to manage chronic diarrhea in people with systemic sclerosis, improving daily comfort and quality of life.

What could go wrong

This is a very small, early pilot study with only 20 people. It mainly checks safety, not whether FMT truly works. Results may not apply to everyone with scleroderma.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diarrheal disease systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Denmark