Engineered immune cells take on autoimmune diseases in first human test
NCT ID NCT06544330
First seen Nov 05, 2025 · Last updated May 13, 2026 · Updated 21 times
Summary
This early-phase study tests a new treatment that uses a patient's own immune cells, modified to target and calm the overactive immune system causing severe lupus or scleroderma. About 48 adults with these hard-to-treat autoimmune diseases will receive the therapy to see if it is safe and tolerable. The main goal is to check for side effects, while also watching for signs that the disease is getting better.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Feinstein Institutes for Medical Research
Manhasset, New York, 11030, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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HonorHealth Research Institute
Scottsdale, Arizona, 85258, United States
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Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
Conditions
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