Engineered immune cells take aim at Hard-to-Treat scleroderma

NCT ID NCT06400303

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 28 times

Summary

This early-stage study tests a new treatment called KYV-101 for people with systemic sclerosis, a disease where the immune system attacks the body, causing skin and organ damage. The therapy uses a patient's own immune cells, modified to target and destroy harmful B cells. The main goals are to check safety and see if it can improve disease symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Northwell Health

    Great Neck, New York, 11021, United States

  • Stanford University Medical Center

    Palo Alto, California, 94305, United States

Conditions

Explore the condition pages connected to this study.