Shingles vaccine shows promise for autoimmune patients in major new study

NCT ID NCT05879419

First seen Jan 08, 2026 · Last updated Jun 16, 2026 · Updated 24 times

Summary

This study looks at whether the Shingrix vaccine is safe and effective for preventing shingles in people with autoimmune rheumatic diseases like rheumatoid arthritis and lupus. About 2,000 patients will receive the vaccine or a placebo, and researchers will monitor for disease flares and immune response. The goal is to see if the vaccine can be used safely in this high-risk group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rheumatology Division of Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo

    São Paulo, São Paulo, 05403-000, Brazil

Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy ankylosing spondylitis Behcet disease dermatomyositis granulomatosis with polyangiitis herpes zoster juvenile dermatomyositis juvenile idiopathic arthritis myositis disease psoriatic arthritis rheumatoid arthritis Sjogren syndrome Spondylarthritis spondyloarthropathy systemic lupus erythematosus systemic sclerosis Systemic Vasculitis vasculitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.