JUVENILE IDIOPATHIC ARTHRITIS

This study tests an experimental oral medication, upadacitinib, in children aged 1 to 17 with systemic juvenile idiopathic arthritis (sJIA), a rare and serious form of arthritis that can affect the whole body. About 90 participants will receive either upadacitinib or the standard…

This study is testing an oral medication called filgotinib in 10 children and teens aged 8 to 17 who have juvenile idiopathic arthritis (JIA). The goal is to see how the drug moves through the body and whether it is safe and tolerable. Participants must have moderately to severel…

This study looks at the long-term safety and effectiveness of the drug baricitinib for children aged 1 to 17 with juvenile idiopathic arthritis (JIA). It includes 190 kids who have already taken baricitinib in a previous study. Researchers will track serious side effects and how …

This study is testing a drug called olokizumab in children aged 2 to 18 with active juvenile idiopathic arthritis, a condition that causes joint pain and swelling. The main goal is to see how the drug moves through the body and to check its safety and effectiveness. About 71 chil…

This study monitors the safety and effectiveness of the drug Cosentyx in Korean patients with three conditions: hidradenitis suppurativa (painful skin boils), pediatric plaque psoriasis (scaly skin patches in children), and juvenile idiopathic arthritis (childhood arthritis). Abo…

This study is for children aged 1 to 17 with systemic juvenile idiopathic arthritis (sJIA), a rare and serious form of arthritis that causes joint swelling and fevers. The purpose is to find the best dose of the drug sarilumab, which helps control inflammation. Researchers will m…

This study looks at whether a Mediterranean diet can improve arthritis symptoms in children by changing the bacteria in their gut. Fifty-four children with juvenile idiopathic arthritis will follow the diet for 8 weeks, with an option to continue for 4 more weeks. Researchers wil…

This study is creating a new tool to help doctors diagnose and choose treatments for autoimmune diseases. Researchers will analyze blood samples from 500 children with autoimmune conditions and healthy children to find patterns in genes and other molecules. The goal is to make di…

This study looks at whether a walking test called the Dynamic Gait Index (DGI) can be used to measure walking problems in children with juvenile idiopathic arthritis (JIA). About 52 children aged 8-16 with JIA and healthy kids will take the test, which includes walking on differe…

This study is working to create a new, objective way to measure pain in children with juvenile arthritis, lupus, or fibromyalgia. Researchers will follow 90 children for one year, collecting data during regular clinic visits. The goal is to replace the current trial-and-error app…

This study looks at how children with juvenile idiopathic arthritis (JIA) experience pain. Researchers will use heat, cold, and pressure tests along with questionnaires to measure pain sensitivity. The goal is to better understand the causes of pain in JIA, which could lead to im…