JUVENILE IDIOPATHIC ARTHRITIS

This study is testing whether following a Mediterranean-style diet for 8-12 weeks can help reduce arthritis disease activity in children. Researchers want to see if dietary changes improve symptoms by altering the community of bacteria in the gut (the microbiome). The study will …

This study is testing a medication called filgotinib in children and teenagers with juvenile idiopathic arthritis (JIA). The main goals are to see how the drug behaves in the body, if it's safe, and if kids can tolerate it. It's an early-phase study for children aged 8 to 18 whos…

This study is testing how well and how safe the drug upadacitinib is for children and teenagers (ages 1 to under 18) with a rare and serious form of childhood arthritis called systemic juvenile idiopathic arthritis (sJIA). It will compare upadacitinib to another existing treatmen…

This study is monitoring the safety and real-world effectiveness of an already-approved drug called Cosentyx (secukinumab) in Korean patients. It will follow 76 people with moderate-to-severe hidradenitis suppurativa (a painful skin condition), pediatric plaque psoriasis, or juve…

This study aims to find the right dose of an injected medication called sarilumab for children and teenagers (ages 1-17) with a severe form of juvenile arthritis. It will test how the drug moves through the body, its safety, and if it helps control the disease. The study includes…

This study is checking the long-term safety and effectiveness of the drug baricitinib in children and teenagers (ages 1 to 17) with juvenile idiopathic arthritis (JIA). It is only for participants who have already been taking baricitinib in a previous related study. The main goal…

This study is testing a walking assessment tool to see if it reliably measures walking difficulties in children with juvenile arthritis. Researchers will compare 52 children with arthritis to healthy children while they perform walking tasks like navigating obstacles and climbing…

This study aims to understand how children with juvenile arthritis experience pain differently than healthy children. Researchers will measure pain sensitivity using pressure and cold tests and collect information about health and lifestyle. The goal is to learn more about the pa…

This study aims to create better tools for diagnosing and treating children with rare, inherited immune system disorders that cause severe autoimmune diseases. Researchers will analyze blood and tissue samples from 500 children to find molecular patterns that predict how their di…