JUVENILE IDIOPATHIC ARTHRITIS

This study tested whether adding leflunomide to standard methotrexate treatment helps children with severe, hard-to-treat arthritis. Fifty children were split into two groups: one received the drug combo, the other methotrexate alone. Researchers tracked disease activity and dail…

This study tested whether a weekly injection of abatacept, given for 24 weeks, could stop mild juvenile arthritis from turning into a more severe form. It involved 121 children ages 2 to 16 with recent-onset arthritis in 4 or fewer joints. The goal was to see if the drug could pr…

This study looked at the long-term safety of the drug tocilizumab (RoActemra/Actemra) in children with a type of arthritis called polyarticular-course juvenile idiopathic arthritis. Seven children who had already finished a main study received the drug every 4 weeks for up to 2 y…

This study looked at whether adding a probiotic (VSL#3) to standard treatment helps children with juvenile idiopathic arthritis (JIA). 51 children aged 1 to 7 with specific types of JIA took part. Researchers measured disease activity and changes in gut bacteria to see if the pro…

This study looked at the long-term safety of the drug tofacitinib in children with juvenile idiopathic arthritis (JIA). It included 302 children who had already taken tofacitinib in earlier studies. Researchers monitored lab tests, side effects, and growth to see how well the dru…

This study looked at 62 children with juvenile idiopathic arthritis whose disease was inactive. Researchers tested whether slowly reducing and then stopping their biologic medication was as safe and effective as staying on the full dose for 24 weeks. The goal was to see if kids c…

This study tested two exercise programs for 54 teens aged 12-18 with juvenile idiopathic arthritis. One group did supervised sessions with a physiotherapist, while the other used a personalized mobile app. Both groups wore smart watches to track activity. The goal was to see whic…

This study tested whether coaching sessions are a practical way to help young people with rheumatic diseases (like juvenile arthritis) move from pediatric to adult rheumatology care. Researchers enrolled 26 patients and measured how many agreed to join, attended sessions, and com…

This study looked at 126 children with juvenile idiopathic arthritis to find the best dose of the drug etanercept. Researchers measured drug levels in the blood and checked how well the arthritis was controlled. The goal was to personalize dosing for each child to improve treatme…

This study looked at whether two newer blood markers (calprotectin and serum amyloid protein) can help doctors monitor disease activity in children with inflammatory rheumatic diseases like juvenile idiopathic arthritis. Researchers measured these alongside standard markers in 20…

This study tested whether a transition coach could help 16-17 year olds with Juvenile Idiopathic Arthritis or Inflammatory Bowel Disease move from pediatric to adult healthcare. 27 teens took part in a coaching program to build self-management skills. The main goal was to see if …