Could a probiotic help kids with arthritis?

NCT ID NCT03092427

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether taking a probiotic called VSL#3, alongside standard treatment, can reduce disease activity in children with juvenile idiopathic arthritis (JIA). Fifty-one children aged 1 to 7 with specific types of JIA took either the probiotic or a placebo. Researchers measured changes in arthritis symptoms and looked at the bacteria in their stool.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Probiotic VSL#3 (a dietary supplement containing live bacteria)
What this could lead to
If it works, this could point toward a simple, safe add-on treatment to help control arthritis in children.
What could go wrong
This is a small, early study with only 51 children. The probiotic may not improve symptoms or change the gut bacteria enough to make a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Robert Debre Hospital

    Paris, 75019, France

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Other studies related to the condition(s) this trial covers.